Role of Janus kinase 1 and signal transducer and activator of transcription 3 in vitiligo

RM Samaka, MA Basha, D Menesy - Clinical, cosmetic and …, 2019 - Taylor & Francis
Background Vitiligo is an acquired autoimmune skin disorder. The often-visible lesions of
vitiligo have a major impact on patients' quality of life and the results of the treatment …

Cutaneous JAK expression in vitiligo

AA Abdel Motaleb, YM Tawfik… - Journal of …, 2021 - journals.sagepub.com
Background The Janus kinase–signal transducer and activator of transcription signaling
pathway has been suggested as a promising therapeutic target in vitiligo. However, limited …

Cutaneous JAK Expression in Vitiligo.

AM AA, YM Tawfik, MA El-Mokhtar… - Journal of Cutaneous …, 2020 - europepmc.org
Background The Janus kinase-signal transducer and activator of transcription signaling
pathway has been suggested as a promising therapeutic target in vitiligo. However, limited …

[HTML][HTML] Immunohistochemistry of Janus kinase 1 (JAK1) expression in vitiligo

AG Abdou, A Maraee, H Yassien… - Journal of Pathology and …, 2018 - ncbi.nlm.nih.gov
Background Vitiligo is a chronic autoimmune disease in which the destruction of
melanocytes causes white spots on the affected skin. Janus kinase (JAK) is a family of …

The use of Janus kinase inhibitors in vitiligo: a review of the literature

N Relke, M Gooderham - Journal of cutaneous medicine …, 2019 - journals.sagepub.com
Vitiligo is a common acquired depigmenting disorder characterized by the development of
white macules and patches due to the loss of melanocytes. Patients with vitiligo can be …

Expression of Janus Kinase 1 in vitiligo & psoriasis before and after narrow band UVB: a case–control study

HR Nada, DA El Sharkawy, MF Elmasry… - Archives of …, 2018 - Springer
Janus kinases (JAKs) are non-receptor protein tyrosine kinases that are expressed in many
tissues. Once the JAKs are activated, a cascade of further signaling events is triggered …

JAK inhibitors in vitiligo: what they hit and what they miss-an immunopathogenesis based exposition of existing evidence

K Sardana, A Muddebihal… - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction Vitiligo is an autoimmune disorder which presents as depigmented macules
due to selective loss of melanocytes. Heightened expression of Janus Kinase Signal …

Vitiligo treatments: review of current therapeutic modalities and JAK inhibitors

KN Cunningham, D Rosmarin - American journal of clinical dermatology, 2023 - Springer
Vitiligo is a chronic autoimmune disease characterized by loss of pigment of the skin,
affecting 0.5–2% of the population worldwide. It can have a significant impact on patients' …

Importance of light in the treatment of vitiligo with JAK-inhibitors

D Joshipura, N Plotnikova, A Goldminz… - Journal of …, 2018 - Taylor & Francis
Vitiligo is an autoimmune pigmentary disorder characterized by depigmented patches of
skin with a selective loss of melanocytes. Recent advances describe vitiligo as a T-helper …

[HTML][HTML] Understanding of pathomechanisms and clinical practice for vitiligo

A Tanemura - Annals of Dermatology, 2023 - ncbi.nlm.nih.gov
Vitiligo is a disease caused by the acquired depletion of melanocytes and/or melanocyte
precursor cells in response to genetic and environmental factors, resulting in …