Tyrosinase is an enzyme widely distributed in nature, which has multiple functions,
especially in the melanin biosynthesis pathway. Despite the few clinically available …

To aid the pharmaceutical and cosmetic industry in the development of alternatives to
prevent melanin-related hyperpigmentation disorders, the plant Dalea elegans was …

Wedelolactone, a benzofuran based natural product that can be isolated from Eclipta
prostrata, exhibits a variety of biological activities. It is inefficient to obtain wedelolactone …

Hedysarimcoumestan B, which can be isolated from Chinese herbal medicine, is achieved,
in which the longest linear sequence is only eight steps, in 50% overall yield from …

Tyrosinase is known as the key enzyme for melanin biosynthesis, which is effective in
preventing skin injury by ultra violet (UV). In past decades, tyrosinase has been well studied …

Tyrosinase plays a key role in the melanin biosynthesis since it catalyzes the transformation
of tyrosine into L-dopaquinone. A large number of studies have also shown that molecules …

Tyrosinase plays crucial roles in mediating the production of melanin pigment; thus, its
inhibitors could be useful in preventing melanin-related diseases. To find potential …

Tyrosinase and its related proteins are responsible for pigmentation disorders, and inhibiting
tyrosinase is an established strategy to treat hyperpigmentation. The carbonyl scaffolds can …

Tyrosinase is a key enzyme for melanin biosynthesis and known to be sensitive to ultraviolet
light in the presence of oxygen. Therefore, finding effective tyrosinase inhibitors, either from …

In our previous study, 8-hydroxydaidzein (8-OHDe) was demonstrated to be a potent and
unique suicide substrate of mushroom tyrosinase. In this study, the compound was …