基于甲基化的年龄推断模型构建与效能评估

李姗飞, 彭付端, 王建宁 - 法医学杂志, 2019 - fyxzz.cn
目的筛选与中国北方汉族男性个体年龄相关的DNA 甲基化位点并构建年龄推断模型.
方法筛选21 个候选甲基化位点, 使用EpiTYPER 技术平台在476 份汉族男性血液DNA …

Methylation-based age estimation model construction and its effectiveness evaluation

LI Shan-fei, P Fu-duan, W Jian-ning - Journal of Forensic Medicine, 2019 - fyxzz.cn
Objective To screen the DNA methylation loci associated with the age of Han males in
northern China and to construct an age estimation model. Methods Twenty-one candidate …

DNA 甲基化推断人类年龄的研究进展

王中华, 李淑瑾 - 法医学杂志, 2020 - fyxzz.cn
在法庭科学实践中, 年龄是重要的个体信息, 是刻画嫌疑人特征首先要考虑的指标之一. 近年来,
DNA 甲基化因其出色的准确性和稳定性成为年龄推断的研究热点. 在DNA 甲基化位点的特异性 …

Accurate age estimation from blood samples of Han Chinese individuals using eight high-performance age-related CpG sites

X Han, C Xiao, S Yi, Y Li, M Chen, D Huang - International Journal of Legal …, 2022 - Springer
Age-related CpG sites (AR-CpGs) are currently the most promising biomarkers for forensic
age estimation. In our previous studies, we first validated the age correlation of seven …

未成年人案件中两种骨龄测定法的应用价值的初步研究

张振, 李开, 余荣军, 张秦初 - 法医学杂志, 2004 - fyxzz.cn
目的研究未成年人骨龄与实际年龄和刑事责任年龄间的关系, 探讨顾氏图谱法,
李果珍骨龄百分计数法在未成年人涉嫌犯罪案件中的应用价值. 方法选择33 位身体健康 …

The correlation between CpG island methylation of hTERT promoter and human age prediction

H Cui, Y Xin, F Cao, Z Gan, Y Tian, W Liu, P Shi - Legal Medicine, 2023 - Elsevier
DNA methylation is an epigenetic modification that occurs during the life cycle of individuals.
Its degree is closely associated with the methylation status of CpG sites in its promoter …

如何正确看待法医骨龄和刑事责任年龄

王鹏, 朱广友, 王新蕾, 范利华, 夏文涛 - 中国司法鉴定, 2008 - chsfjd.cn
骨龄又叫骨骼测定年龄, 刑法所规定的" 刑事责任年龄" 为某一个体的" 生活年龄",
二者所代表的含义不同, 且存在着较大的差异. 司法机关直接利用骨龄作为对犯罪嫌疑人定罪 …

Systematic feature selection improves accuracy of methylation-based forensic age estimation in Han Chinese males

L Feng, F Peng, S Li, L Jiang, H Sun, A Ji… - Forensic Science …, 2018 - Elsevier
Estimating individual age from biomarkers may provide key information facilitating forensic
investigations. Recent progress has shown DNA methylation at age-associated CpG sites as …

The evaluation of seven age-related CpGs for forensic purpose in blood from Chinese Han population

C Pan, S Yi, C Xiao, Y Huang, X Chen… - Forensic Science …, 2020 - Elsevier
Age prediction of biological samples is one of the important tasks in forensic DNA
phenotyping, and DNA methylation is regarded as the most promising biomarker for forensic …

[引用][C] DNA 甲基化水平的法医学个体年龄推断

贾菲, 孙学科, 喻少波, 于蛟, 林春美, 阚旭升, 邵武 - 中国法医学杂志, 2021