Transcriptional and in silico analyses of MIF cytokine and TLR signalling interplay in the LPS inflammatory response of Ciona robusta

V Arizza, A Bonura, L La Paglia, A Urso, A Pinsino… - Scientific Reports, 2020 - nature.com
The close phylogenetic relationship between Ciona robusta and vertebrates makes it a
powerful model for studying innate immunity and the evolution of immune genes. To …

TAK1 inhibitor enhances the therapeutic treatment for glioblastoma

M Campolo, M Lanza, G Casili, I Paterniti, A Filippone… - Cancers, 2020 - mdpi.com
Simple Summary Most patients with glioblastoma (GBM) develop recurrent diseases which
can be treated with different approaches. Given the aggressive and resilient nature of GBM …

Parthenolide and its analogues: a new potential strategy for the treatment of triple-negative breast tumors

TG Araujo, L Vecchi, PMAP Lima… - Current Medicinal …, 2020 - ingentaconnect.com
Triple Negative Breast Cancers (TNBC) are heterogeneous and aggressive pathologies,
with distinct morphological and clinical characteristics associated with their genetic diversity …

Knockdown of LAP2α inhibits osteogenic differentiation of human adipose-derived stem cells by activating NF-κB

Y Tang, X Zhang, W Ge, Y Zhou - Stem Cell Research & Therapy, 2020 - Springer
Background Lamina-associated polypeptide 2α (LAP2α) is a nucleoplasmic protein that has
been involved in the regulation of the cell cycle, gene transcription, and adult stem cell …

Longshengzhi Capsules Improve Ischemic Stroke Outcomes and Reperfusion Injury via the Promotion of Anti‐Inflammatory and Neuroprotective Effects in MCAO/R …

W Yang, L Zhang, S Chen, Q Yao… - Evidence‐Based …, 2020 - Wiley Online Library
Stroke is the leading cause of death in the elderly. Traditional Chinese medicine provides an
exciting strategy for treating stroke. Previous reports indicated that Longshengzhi capsules …

MerTK negatively regulates Staphylococcus aureus induced inflammatory response via Toll-like receptor signaling in the mammary gland

A Zahoor, Y Yang, C Yang, SB Khan, C Reix… - Molecular …, 2020 - Elsevier
Mastitis is the most commonly diagnosed infectious disease reducing milk yield and quality
and is accompanied by mammary tissue damage in both humans and animals. Mastitis …

Mathematical modeling of canonical and non-canonical NF-κB pathways in TNF stimulation

B Ji, Y Zhang, C Zhen, MJ Fagan, Q Yang - Computer Methods and …, 2020 - Elsevier
Background and objective NF-κB can be activated by the canonical and non-canonical
pathways. These two pathways interplay via the TRAF1| NIK complex after stimulation by …

[HTML][HTML] Mucosa-associated lymphoid tissue lymphoma of various sites: Common molecular mechanisms but different players

MQ Du - Annals of Lymphoma, 2020 - aol.amegroups.org
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT)
commonly arises from a background of chronic inflammatory disorder at various mucosal …

Psoriasis-From Transcriptome to miRna Function and Biomarkers

L Pasquali - 2020 - search.proquest.com
Psoriasis is a chronic inflammatory, immune-mediated skin condition that affects in average
2 to 3% of the world population, phenotypically characterized by red and scaly plaques on …

[图书][B] In vitro co-targeting of PARP-1 and HDAC-1 in prostate cells of varying maspin status

JA Toomey - 2020 - search.proquest.com
Prostate cancer is the most common form of cancer in males. In the UK, 1 in 8 males will
develop prostate cancer in their lifetime, making research into this condition important …