Expression and clinical significance of immune checkpoint regulator B7-H3 (CD276) in human meningioma

J Deng, M Ma, D Wang, H Zhu, L Hua, S Sun, H Chen… - World neurosurgery, 2020 - Elsevier
Background The high expression across multiple tumor types and restricted expression in
normal tissues make B7-H3 an attractive target for immunotherapy. So far, little is known …

Natural history of intracranial meningiomas

CA Glenn, HJ Tullos, ME Sughrue - Handbook of clinical neurology, 2020 - Elsevier
We know that the extent of resection is the greatest predictor of long-term survival. However,
the potential tradeoff for gross total resection in difficult locations is diminished quality of life …

Low expression of phosphatase and tensin homolog and high expression of Ki-67 as risk factors of prognosis in cranial meningiomas

J Ma, Y Zhang, L Chen, Y Chen, Y Yang, D Li… - World Neurosurgery, 2020 - Elsevier
Objective To investigate the expression characteristics, correlations with clinical factors, and
prognostic values of phosphatase and tensin homolog (PTEN) and Ki-67 in cranial …

Olfactory groove and planum meningiomas

F DeMonte, SM Raza - Handbook of Clinical Neurology, 2020 - Elsevier
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Paediatric meningiomas in Singapore—Case series of a rare entity

D Thevandiran, V Nga, KTE Chang, LP Ng… - Journal of Clinical …, 2020 - Elsevier
Paediatric meningiomas are extremely rare. These tumours constitute only 2 to 3% of all
childhood brain tumours. Despite similarities in histological features between PMs and their …

Medical management of meningiomas

UN Chukwueke, PY Wen - Handbook of Clinical Neurology, 2020 - Elsevier
Meningiomas are the most frequently occurring primary brain tumors in adults, representing
almost one-third of all primary central nervous system tumors. Several factors have been …

Current decision-making in meningiomas

MN Pamir, K Özduman - Handbook of clinical neurology, 2020 - Elsevier
The incidence of meningiomas is rising and the number of incidental cases is increasing
steadily. The efficiency and the safety of each treatment strategy are also improving over …

Copy number assessment in the genomic analysis of CNS neoplasia: an evidence-based review from the cancer genomics consortium (CGC) working group on …

SG Neill, J Hauenstein, MM Li, YJ Liu, M Luo, DF Saxe… - Cancer Genetics, 2020 - Elsevier
The period from the 1990s to the 2010s has witnessed a burgeoning sea change in the
practice of surgical neuropathology due to the incorporation of genomic data into the …

Molecular advances in central nervous system mesenchymal tumors

J Helgager, J Driver, S Hoffman, WL Bi - Surgical Pathology Clinics, 2020 - Elsevier
Mesenchymal tumors of the central nervous system (CNS) comprise an array of neoplasms
that may arise from or secondarily affect the CNS and its immediate surroundings. This …

Meningioma epigenetic grouping reveals biologic drivers and therapeutic vulnerabilities

D Raleigh, S Magill, C Eaton, B Prager, W Chen, K Seo… - 2020 - researchsquare.com
Meningiomas arising from the meningothelial central nervous system lining are the most
common primary intracranial tumors, and a significant cause of neurologic morbidity and …