Protein-protein interactions play a vital role in nearly all cellular functions. Hence,
understanding their interaction patterns and three-dimensional structural conformations can …

Cross-linking mass spectrometry is an increasingly used, powerful technique to study
protein–protein interactions or to provide structural information. Due to substochiometric …

Fourier transform ion cyclotron resonance mass spectrometry (FTICR–MS) is a powerful
instrument for high-resolution analysis of biomolecules. However, relatively long signal …

Mass spectrometry (MS) has long been used to study proteins mainly via sequence
identification and quantitation of expression abundance. In recent years, MS has emerged …

Cross-linking mass spectrometry (XL-MS) is steadily expanding its range of applications
from purified protein complexes to more complex samples like organelles and even entire …

Provided herein are compositions and methods for inhibiting cancer cell motility and/or
metastasis. In particular embodiments, KBU2046 (or an analog thereof) and one or more …

Cross-linking mass spectrometry (XL-MS) has attracted broad attention because of the
capability to probe three-dimensional structure of proteins. Up to now, several amine …

Saccharomyces cerevisiae can generate energy in form of ATP either by fermenting or by
respiring nutrition. This depends on the availability of fermentable or non-fermentable …

Triple-negative breast cancer (TNBC) accounts for approximately 15-20% of all breast
cancer cases. It tends to be aggressive, high-grade and poorly differentiated tumour with …

Proteins are the fundamental functional units underlying all cellular activities. Protein
function emerges from structure. To understand cellular activity and the diseases that arise …