[HTML][HTML] Anaplastic lymphoma kinase rearrangement may increase the incidence of venous thromboembolism by increasing tissue factor expression in advanced lung …
S Yang, L Yang, Y Wu, C Zhang, S Wang… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Patients with lung cancer are at an increased risk for venous thromboembolism
(VTE). Approximately 8–15% of patients with advanced non-small-cell lung cancer (NSCLC) …
(VTE). Approximately 8–15% of patients with advanced non-small-cell lung cancer (NSCLC) …
Therapeutic landscape of metastatic non-small-cell lung cancer in Canada in 2020
Lung cancer is the most commonly diagnosed cancer in Canada and remains associated
with high mortality. Nevertheless, recent advances in the fields of immuno-oncology and …
with high mortality. Nevertheless, recent advances in the fields of immuno-oncology and …
[HTML][HTML] Non-small cell lung cancer from genomics to therapeutics: A framework for community practice integration to arrive at personalized therapy strategies
S Rajurkar, I Mambetsariev, R Pharaon… - Journal of Clinical …, 2020 - mdpi.com
Non-small cell lung cancer (NSCLC) is a heterogeneous disease, and therapeutic
management has advanced with the identification of various key oncogenic mutations that …
management has advanced with the identification of various key oncogenic mutations that …
[HTML][HTML] Does pemetrexed work in targetable, nonsquamous non-small-cell lung cancer? A narrative review
JY Shih, A Inoue, R Cheng, R Varea, SW Kim - Cancers, 2020 - mdpi.com
Simple Summary The chemotherapy agent pemetrexed is currently considered in
combination with other therapies for the treatment of advanced nonsquamous non-small-cell …
combination with other therapies for the treatment of advanced nonsquamous non-small-cell …
Efficacy and safety of ALK inhibitors in ALK-rearranged non-small cell lung cancer: a systematic review and meta-analysis
D Breadner, P Blanchette, S Shanmuganathan… - Lung Cancer, 2020 - Elsevier
Objectives No overall survival (OS) benefit has been reported from a mature randomized
trial with the use of ALK inhibitors. We conducted a systematic review and meta-analysis to …
trial with the use of ALK inhibitors. We conducted a systematic review and meta-analysis to …
[HTML][HTML] Coexistence of a novel CCNY-ALK and ATIC-ALK double-fusion in one patient with ALK-positive NSCLC and response to crizotinib: a case report
X Wu, H Zhou, Z He, Z Zhang, W Feng… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
Anaplastic lymphoma kinase (ALK) rearrangement, one of the common oncogene
rearrangements in the mutational history of lung adenocarcinoma, occurs in approximately …
rearrangements in the mutational history of lung adenocarcinoma, occurs in approximately …
[HTML][HTML] Prevalence and clinical impact of concomitant mutations in anaplastic lymphoma kinase rearrangement advanced non-small-cell lung cancer (Guangdong …
M Li, X Hou, C Zhou, W Feng, G Jiang, H Long… - Frontiers in …, 2020 - frontiersin.org
Background: In patients with anaplastic lymphoma kinase (ALK) rearrangement-positive
advanced non–small-cell lung cancer (NSCLC), ALK inhibitors are now the standard …
advanced non–small-cell lung cancer (NSCLC), ALK inhibitors are now the standard …
Paired genetic analysis by next‐generation sequencing of lung cancer and associated idiopathic pulmonary fibrosis
K Otsubo, E Iwama, K Ijichi, N Kubo… - Cancer …, 2020 - Wiley Online Library
The pathogenesis of lung cancer associated with idiopathic pulmonary fibrosis (IPF) has
remained largely uncharacterized. To provide insight into this condition, we undertook …
remained largely uncharacterized. To provide insight into this condition, we undertook …
[HTML][HTML] Molecular profiling of non-small cell lung cancer
ML Forsythe, A Alwithenani, D Bethune… - PLoS …, 2020 - journals.plos.org
Lung cancer is generally treated with conventional therapies, including chemotherapy and
radiation. These methods, however, are not specific to cancer cells and instead attack every …
radiation. These methods, however, are not specific to cancer cells and instead attack every …
A trial of the safety and efficacy of chemotherapy plus anlotinib vs chemotherapy alone as second-or third-line salvage treatment for advanced non-small cell lung …
H Wang, J Chu, Y Zhao, H Tang, L Wang… - Cancer Management …, 2020 - Taylor & Francis
Purpose Anlotinib is a newly developed oral multitarget tyrosine kinase inhibitor. We
retrospectively evaluated the toxicity and clinical efficacy of chemotherapy combined with …
retrospectively evaluated the toxicity and clinical efficacy of chemotherapy combined with …