Embryo-derived and induced pluripotent stem cells: Towards naive pluripotency and chimeric competency in rabbits

M Afanassieff, F Perold, W Bouchereau… - Experimental Cell …, 2020 - Elsevier
Both embryo-derived (ESC) and induced pluripotent stem cell (iPSC) lines have been
established in rabbit. They exhibit the essential characteristics of primed pluripotency. In this …

p38-MAPK mediated rRNA processing and translation regulation enables PrE differentiation during mouse blastocyst maturation

P Bora, L Gahurova, T Mašek, A Hauserova, D Potěšil… - bioRxiv, 2020 - biorxiv.org
Background p38-MAPKs are stress-activated kinases necessary for placental development
and nutrient and oxygen transfer during murine post-implantation development. In …

The combined action of Esrrb and Nr5a2 is essential for naïve pluripotency

N Festuccia, N Owens, A Chervova, A Dubois… - bioRxiv, 2020 - biorxiv.org
The maintenance of pluripotency in mouse embryonic stem cells (ESCs) is governed by the
action of an interconnected network of transcription factors. Among them, only Oct4 and …

Npac Is a Co-factor of Histone H3K36me3 and Regulates Transcriptional Elongation in Mouse ES Cells

S Yu, J Li, G Ji, ZL Ng, J Siew, WN Lo, Y Ye, YY Chew… - BioRxiv, 2020 - biorxiv.org
Chromatin modification contributes to pluripotency maintenance in embryonic stem cells
(ESCs). However, the related mechanisms remain obscure. Here, we show that Npac, a …

Universal early cancer diagnostics

A Meissner, ZD Smith, F Michor, J Shi - US Patent App. 16/613,114, 2020 - Google Patents
2023-04-24 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

[PDF][PDF] Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired

W Fu, Y Yue, K Miao, G Xi, C Zhang, W Wang, L An… - hypertension - ijbs.com
Well-orchestrated epigenetic modifications during early development are essential for
embryonic survival and postnatal growth. Erroneous epigenetic modifications due to …

[PDF][PDF] Distinct requirements for the maintenance and

小西, 理予 - 2020 - ir.library.osaka-u.ac.jp
Mouse embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of
blastocysts. The culture condition with the cytokine leukemia inhibitory factor (LIF) and two …

[PDF][PDF] Characterization of rabbit embryo-derived cells grown under conditions promoting naïve mouse pluripotency.

A Catalina Konarska-Diaz, A Bernat, A Bihorac… - Animal Science Papers …, 2020 - igbzpan.pl
196 similar to naïve mouse ESCs, with the high and homogenous expression of pluripotency
factors NANOG, SOX2, KLF4 and OCT4. However, 2i conditions were only sufficient for the …

Tuneable Cell Substrates

CC Agley, K Chalut, JCR Da Silva - US Patent App. 16/772,584, 2020 - Google Patents
2020-10-27 Assigned to CAMBRIDGE ENTERPRISE LIMITED reassignment CAMBRIDGE
ENTERPRISE LIMITED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …