Cocaine-induced structural and functional impairments of the glymphatic pathway in mice
W Chen, P Huang, H Zeng, J Lin, Z Shi… - Brain, Behavior, and …, 2020 - Elsevier
The glymphatic system plays a central role in the clearance of extracellular wastes from the
brain. Cocaine exposure can lead to pathologies that affect the entire brain, resulting in …
brain. Cocaine exposure can lead to pathologies that affect the entire brain, resulting in …
Enhanced neuronal and blunted hemodynamic reactivity to cocaine in the prefrontal cortex following extended cocaine access: optical imaging study in anesthetized …
Cocaine addiction is associated with dysfunction of the prefrontal cortex (PFC), which
facilitates relapse and compulsive drug taking. To assess if cocaine's effects on both …
facilitates relapse and compulsive drug taking. To assess if cocaine's effects on both …
A novel conceptual framework for the functionality of the glymphatic system
K Astara, C Pournara, ER de Natale… - Journal of …, 2023 - journals.physiology.org
The glymphatic system is responsible for the clearance of the potentially harmful metabolic
waste of the central nervous system. The prevalent theory is that the cerebrospinal fluid …
waste of the central nervous system. The prevalent theory is that the cerebrospinal fluid …
Chronic stress impairs the aquaporin-4-mediated glymphatic transport through glucocorticoid signaling
Background The glymphatic system has recently been proposed to function as a brain-wide
macroscopic system for the clearance of potentially harmful molecules, such as amyloid beta …
macroscopic system for the clearance of potentially harmful molecules, such as amyloid beta …
Glymphatic system: an emerging therapeutic approach for neurological disorders
Y Gao, K Liu, J Zhu - Frontiers in Molecular Neuroscience, 2023 - frontiersin.org
The functions of the glymphatic system include clearance of the metabolic waste and
modulation of the water transport in the brain, and it forms a brain-wide fluid network along …
modulation of the water transport in the brain, and it forms a brain-wide fluid network along …
The glymphatic system: implications for drugs for central nervous system diseases
TJ Lohela, TO Lilius, M Nedergaard - Nature Reviews Drug Discovery, 2022 - nature.com
In the past decade, evidence for a fluid clearance pathway in the central nervous system
known as the glymphatic system has grown. According to the glymphatic system concept …
known as the glymphatic system has grown. According to the glymphatic system concept …
Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia
LM Hablitz, HS Vinitsky, Q Sun, FF Stæger… - Science …, 2019 - science.org
The glymphatic system is responsible for brain-wide delivery of nutrients and clearance of
waste via influx of cerebrospinal fluid (CSF) alongside perivascular spaces and through the …
waste via influx of cerebrospinal fluid (CSF) alongside perivascular spaces and through the …
Repetitive mild traumatic brain injury alters glymphatic clearance rates in limbic structures of adolescent female rats
The glymphatic system is the macroscopic waste clearance system for the central nervous
system. Glymphatic dysfunction has been linked to several neurological conditions …
system. Glymphatic dysfunction has been linked to several neurological conditions …
Chronic cocaine administration causes extensive white matter damage in brain: diffusion tensor imaging and immunohistochemistry studies
PA Narayana, JJ Herrera, KH Bockhorst… - Psychiatry Research …, 2014 - Elsevier
The effect of chronic cocaine exposure on multiple white matter structures in rodent brain
was examined using diffusion tensor imaging (DTI), locomotor behavior, and end point …
was examined using diffusion tensor imaging (DTI), locomotor behavior, and end point …
The brain's glymphatic system: drawing new perspectives in neuroscience
AV Ciurea, AG Mohan, RA Covache-Busuioc… - Brain Sciences, 2023 - mdpi.com
This paper delves into the intricate structure and functionality of the brain's glymphatic
system, bringing forth new dimensions in its neuroscientific understanding. This paper …
system, bringing forth new dimensions in its neuroscientific understanding. This paper …