[PDF][PDF] Excessive folic acid supplementation in pregnant mice impairs insulin secretion and induces the expression of genes associated with fatty liver in their offspring
Y Kintaka, N Wada, S Shioda, S Nakamura… - Heliyon, 2020 - cell.com
Objective Previous human and animal studies have shown that excessive maternal intake of
folic acid (FA) predisposes to impaired glucose tolerance in the offspring. However, the …
folic acid (FA) predisposes to impaired glucose tolerance in the offspring. However, the …
[HTML][HTML] Maternal high folic acid supplement promotes glucose intolerance and insulin resistance in male mouse offspring fed a high-fat diet
Maternal nutrition may influence metabolic profiles in offspring. We aimed to investigate the
effect of maternal folic acid supplement on glucose metabolism in mouse offspring fed a high …
effect of maternal folic acid supplement on glucose metabolism in mouse offspring fed a high …
Maternal and postweaning folic acid supplementation interact to influence body weight, insulin resistance, and food intake regulatory gene expression in rat offspring …
PSP Huot, A Ly, IMY Szeto… - Applied Physiology …, 2016 - cdnsciencepub.com
Maternal intake of multivitamins or folic acid above the basal dietary requirement alters the
growth and metabolic trajectory of rat offspring. We hypothesized that a modest increase in …
growth and metabolic trajectory of rat offspring. We hypothesized that a modest increase in …
High-dose perinatal folic-acid supplementation alters insulin sensitivity in Sprague-Dawley rats and diminishes the expression of adiponectin
The possible intake of folate in excess of the recommended upper levels is a matter of
critical importance. This study was conducted to investigate the effects of prenatal and …
critical importance. This study was conducted to investigate the effects of prenatal and …
Metabolic effects of a high‐fat diet post‐weaning after low maternal dietary folate during pregnancy and lactation
JA McKay, L Xie, C Manus, SAS Langie… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Investigate the influence of low‐folate supply during pregnancy and lactation on
obesity and markers of the metabolic syndrome in offspring, and how provision of a high‐fat …
obesity and markers of the metabolic syndrome in offspring, and how provision of a high‐fat …
[HTML][HTML] Maternal Prenatal Folic Acid Supplementation Programs Offspring Lipid Metabolism by Aberrant DNA Methylation in Hepatic ATGL and Adipose LPL in Rats
The effects of maternal prenatal folic acid supplementation (FAS) on offspring lipid
metabolism in adulthood remains unclear, although prenatal FAS is compulsively suggested …
metabolism in adulthood remains unclear, although prenatal FAS is compulsively suggested …
[HTML][HTML] Effects of folic acid supplementation in pregnant mice on glucose metabolism disorders in male offspring induced by lipopolysaccharide exposure during …
WX Sun, YP Shu, XY Yang, W Huang, J Chen… - Scientific Reports, 2023 - nature.com
The DOHaD theory suggests that adverse environmental factors in early life may lead to the
development of metabolic diseases including diabetes and hypertension in adult offspring …
development of metabolic diseases including diabetes and hypertension in adult offspring …
Maternal folate status and obesity/insulin resistance in the offspring: a systematic review
RH Xie, YJ Liu, R Retnakaran, AJ MacFarlane… - International Journal of …, 2016 - nature.com
OBJECTIVE: Prenatal folic acid supplementation or maternal folate sufficiency may protect
the offspring from obesity and insulin resistance. This study aims to summarize the findings …
the offspring from obesity and insulin resistance. This study aims to summarize the findings …
[HTML][HTML] Protein and folic acid content in the maternal diet determine lipid metabolism and response to high-fat feeding in rat progeny in an age-dependent manner
A Chmurzynska, M Stachowiak, J Gawecki… - Genes & nutrition, 2012 - Springer
Maternal diet during gestation can exert a long-term effect on the progeny's health by
programming their developmental scheme and metabolism. The aim of this study is to …
programming their developmental scheme and metabolism. The aim of this study is to …
[HTML][HTML] Folate treatment of pregnant rat dams abolishes metabolic effects in female offspring induced by a paternal pre-conception unhealthy diet
J Li, YP Lu, O Tsuprykov, AA Hasan, C Reichetzeder… - Diabetologia, 2018 - Springer
Aims/hypothesis Paternal high-fat diet prior to mating programmes impaired glucose
tolerance in female offspring. We examined whether the metabolic consequences in …
tolerance in female offspring. We examined whether the metabolic consequences in …
相关搜索
- pregnant mice expression of genes
- pregnant mice fatty liver
- expression of genes fatty liver
- pregnant mice insulin secretion
- expression of genes insulin secretion
- fatty liver insulin secretion
- gene expression rat offspring
- folic acid maternal diet
- pregnant mice male offspring
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- folic acid lipid metabolism
- mouse offspring insulin resistance
- gene expression food intake
- pregnant mice lipopolysaccharide exposure
- expression of adiponectin insulin sensitivity
- gene expression body weight