Recombinant porcine FVIII for bleed treatment in acquired hemophilia A: findings from a single-center, 18-patient cohort
P Ellsworth, SL Chen, RS Kasthuri, NS Key… - Blood …, 2020 - ashpublications.org
Acquired hemophilia A (AHA) is a rare bleeding disorder in which acquired autoantibodies
to endogenous factor VIII (FVIII) decrease FVIII activity and lead to a bleeding phenotype. A …
to endogenous factor VIII (FVIII) decrease FVIII activity and lead to a bleeding phenotype. A …
Efficacy and safety of OBI‐1, an antihaemophilic factor VIII (recombinant), porcine sequence, in subjects with acquired haemophilia A
R Kruse‐Jarres, J St‐Louis, A Greist, A Shapiro… - …, 2015 - Wiley Online Library
Acquired haemophilia A (AHA) is a rare bleeding disorder caused by autoantibodies against
human factor VIII (hFVIII). OBI‐1 is an investigational, B‐domain deleted, recombinant FVIII …
human factor VIII (hFVIII). OBI‐1 is an investigational, B‐domain deleted, recombinant FVIII …
Porcine recombinant factor VIII (Obizur; OBI‐1; BAX 801): product characteristics and preclinical profile
D Lillicrap, A Schiviz, C Apostol, P Wojciechowski… - …, 2016 - Wiley Online Library
Introduction Acquired haemophilia A (AHA) is a rare, often severe, auto‐immune bleeding
disorder caused by the development of inhibitory antibodies (inhibitors) to factor VIII (FVIII) …
disorder caused by the development of inhibitory antibodies (inhibitors) to factor VIII (FVIII) …
Recombinant porcine sequence factor VIII (rp FVIII) for acquired haemophilia A: practical clinical experience of its use in seven patients
Introduction A recombinant porcine factor VIII B‐domain‐deleted product (rp FVIII; OBIZUR,
Baxalta Incorporated, Deerfield, IL 60015, USA) was recently approved for treatment of …
Baxalta Incorporated, Deerfield, IL 60015, USA) was recently approved for treatment of …
Acquired haemophilia A treated with recombinant porcine factor VIII: a single centre UK experience.
D Khan, S Raza‐Burton, P Baker… - British Journal of …, 2020 - search.ebscohost.com
Recombinant porcine factor VIII (rpFVIII; Obizur, Susoctocog-alfa) was commissioned by
NHS England in June 2018 as a first line treatment option for actively bleeding patients with …
NHS England in June 2018 as a first line treatment option for actively bleeding patients with …
[HTML][HTML] Cross‐reacting inhibitors against recombinant porcine factor VIII in acquired hemophilia A: data from the GTH‐AH 01/2010 Study
H Türkantoz, C Königs, P Knöbl, R Klamroth… - Journal of Thrombosis …, 2020 - Elsevier
Background Recombinant porcine factor VIII (rpFVIII, OBI‐1, susoctocog alfa) is used for the
treatment of acute bleeds in patients with acquired hemophilia A (AHA). Inhibitors in AHA …
treatment of acute bleeds in patients with acquired hemophilia A (AHA). Inhibitors in AHA …
Review of recombinant anti-haemophilic porcine sequence factor VIII in adults with acquired haemophilia A
E Fosbury, A Drebes, A Riddell… - Therapeutic Advances …, 2017 - journals.sagepub.com
Acquired haemophilia A (AHA) is a rare, serious bleeding disorder most often encountered
in elderly patients. The mainstay of haemostatic management is with bypassing agents …
in elderly patients. The mainstay of haemostatic management is with bypassing agents …
[HTML][HTML] Recombinant porcine factor VIII: Lessons from the past and place in the management of hemophilia A with inhibitors in 2021
Y Dargaud, C Escuriola‐Ettingshausen - Research and Practice in …, 2021 - Elsevier
The most serious complication of factor VIII (FVIII) replacement therapy is the occurrence of
anti‐FVIII alloantibodies that can strongly reduce or abolish the effect of human FVIII …
anti‐FVIII alloantibodies that can strongly reduce or abolish the effect of human FVIII …
Acquired hemophilia A: emerging treatment options
M Janbain, CA Leissinger… - Journal of Blood …, 2015 - Taylor & Francis
Acquired hemophilia A is a rare autoimmune disorder caused by an autoantibody (inhibitor)
to factor VIII (FVIII) that interferes with its coagulant function and predisposes to severe …
to factor VIII (FVIII) that interferes with its coagulant function and predisposes to severe …
Laboratory coagulation tests and recombinant porcine factor VIII: A United Kingdom Haemophilia Centre Doctors' Organisation guideline
A Bowyer, E Gray, A Lowe, P Murphy, S Platton… - …, 2022 - Wiley Online Library
Abstract Introduction Acquired haemophilia A (AHA) is a rare bleeding disorder caused by
development of auto‐antibodies to endogenous coagulation factor VIII (FVIII). Recombinant …
development of auto‐antibodies to endogenous coagulation factor VIII (FVIII). Recombinant …