BACKGROUND Early diagnosis of tuberculosis (TB) and identification of strains of
Mycobacterium tuberculosis resistant to anti-TB drugs are considered the main factors for …

Mycobacterium tuberculosis is the bacterium that causes tuberculosis (TB), a leading cause
of death from infectious disease worldwide. Rapid diagnosis of resistant strains is important …

Early diagnosis of tuberculosis is of major clinical importance. Among 4733 clinical
specimens collected from 3363 patients and subjected to Ziehl-Neelsen microscopy, 4109 …

BACKGROUND To cope with the emergence of multidrug-resistant tuberculosis (MDR-TB),
new molecular methods that can routinely be used to screen for a wide range of drug …

Objectives The objectives of our study were 1) to define risk factors for antimicrobial-resistant
Mycobacterium tuberculosis (MTB) 2) to evaluate the use of real-time PCR-based technique …

BACKGROUND To cope with the emergence of multidrug-resistant tuberculosis (MDR-TB),
new molecular methods that can routinely be used to screen for a wide range of drug …

Tuberculosis remains one of the leading infectious causes of death worldwide. The
emergence of drug-resistant strains of Mycobacterium tuberculosis is a serious public health …

We analysed mutations in katG, inhA and rpoB genes, and isoniazid phenotypic resistance
levels in Mycobacterium tuberculosis isolates from drug-resistant TB patients from São …

Incorporation of rapid detection systems to identify mutations in M. tuberculosis complex that
confer resistance to isoniazid and rifampicin has potentiated the knowledge of their …

Mutations in the katG gene have been identified and correlated with isoniazid (INH)
resistance in Mycobacterium tuberculosis isolates. The mutation AGC→ ACC (Ser→ Thr) at …