Sulfur compounds inhibit high glucose-induced inflammation by regulating NF-κB signaling in human monocytes

ES Jo, N Sp, DY Kang, A Rugamba, IH Kim, SW Bae… - Molecules, 2020 - mdpi.com
High glucose-induced inflammation leads to atherosclerosis, which is considered a major
cause of death in type 1 and type 2 diabetic patients. Nuclear factor-kappa B (NF-κB) plays a …

Non-toxic sulfur inhibits LPS-induced inflammation by regulating TLR-4 and JAK2/STAT3 through IL-6 signaling

DY Kang, N Sp, ES Jo, A Rugamba… - Molecular …, 2021 - spandidos-publications.com
Abstract Janus kinase 2 (JAK2) and STAT3 signaling is considered a major pathway in
lipopolysaccharide (LPS)‑induced inflammation. Toll‑like receptor 4 (TLR‑4) is an …

Natural sulfurs inhibit LPS-induced inflammatory responses through NF-κB signaling in CCD-986Sk skin fibroblasts

N Sp, DY Kang, HD Kim, A Rugamba, ES Jo, JC Park… - Life, 2021 - mdpi.com
Lipopolysaccharide (LPS)-induced inflammatory response leads to serious damage, up to
and including tumorigenesis. Natural mineral sulfur, non-toxic sulfur (NTS), and …

Sodium hydrosulfide inhibiting endothelial cells injury and neutrophils activation via IL-8/CXCR2/ROS/NF-κB axis in type 1 diabetes mellitus rat

X Zhong, X Zhao, L Zhang, N Liu, S Shi… - … and Biophysical Research …, 2022 - Elsevier
Abstract Aims Hydrogen sulfide (H 2 S) prevents endothelial cells injury. However, the
complicated mechanism of sodium hydrosulfide (NaHS, a donor that produces H 2 S) which …

Sulfuretin protects against cytokine-induced β-cell damage and prevents streptozotocin-induced diabetes

MY Song, GS Jeong, KB Kwon, SO Ka… - … & molecular medicine, 2010 - nature.com
NF-κB activation has been implicated as a key signaling mechanism for pancreatic β-cell
damage. Sulfuretin is one of the main flavonoids produced by Rhus verniciflua, which is …

Organosulfur compounds: A review of their anti-inflammatory effects in human health

RT Ruhee, LA Roberts, S Ma, K Suzuki - Frontiers in nutrition, 2020 - frontiersin.org
Phytonutrients are widely recognized for providing protective human health benefits. Among
the phytonutrients, epidemiological and experimental studies show that dietary organosulfur …

Diallyl trisulfide alleviates dextran sulphate sodium‐induced colitis in mice by inhibiting NLRP3 inflammasome activation via ROS/Trx‐1 pathway

Y He, L Xiao, J Zhang, Y Zhu, Y Guo… - Basic & Clinical …, 2024 - Wiley Online Library
Diallyl trisulfide (DATS), a sulphur‐containing compound isolated from the medicinal food
plant garlic, has been previously reported to attenuate experimental colitis induced by either …

Hydrogen sulfide mitigates myocardial inflammation by inhibiting nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome activation in …

Q Jia, S Mehmood, X Liu, S Ma… - … Biology and Medicine, 2020 - journals.sagepub.com
Inflammation plays a crucial part in hyperglycemia-induced myocardial damage. Hydrogen
sulfide has been found to possess multiple biological activities in previous studies. This …

Diallyl trisulfide exerts anti-inflammatory effects in lipopolysaccharide-stimulated RAW 264.7 macrophages by suppressing the Toll-like receptor 4/nuclear factor-κB …

HH Lee, MH Han, HJ Hwang… - International …, 2015 - spandidos-publications.com
Diallyl trisulfide (DATS; di-2-propen-1-yl trisulfide) is an organic polysulfide compound found
in garlic and other allium vegetables. Although certain studies have demonstrated that DATS …

Macrophage activity under hyperglycemia: a study of the effect of resveratrol and 3h-1, 2-dithiole-3-thione on potential polarization

J Manríquez-Núñez, O Mora, F Villarroya… - Molecules, 2023 - mdpi.com
Currently, research is focused on bioactive compounds with the potential to promote
macrophage polarization with the aim of reducing the development of inflammatory-related …