Meningiomas are common in adults (~ 35% of brain tumors) but rare in children, where they
exhibit unique clinical, pathological and molecular features compared to adult counterparts …

Background Meningiomas have always represented the most frequently observed primary
central nervous system (CNS) tumor in adults. Multiple advances concerning the genetic …

Molecular and clinical characteristics of pediatric meningiomas are poorly defined.
Therefore, we analyzed clinical, morphological and molecular profiles of pediatric …

In contrast to adults, meningiomas are uncommon tumors in childhood and adolescence.
Whether adult and pediatric meningiomas differ on a molecular level is unclear. Here we …

Pediatric meningiomas, which account for< 1% of all meningiomas, are thought to have
unique features, including being more aggressive than their adult counterparts. The goal of …

With improvement in leukemia therapy, central nervous system (CNS) tumors are the
leading cause of cancer mortality in children and the most expensive of all human …

Accurate risk stratification for meningioma patients is challenging, particularly with
borderline histology between WHO grade 1 and 2. Several molecular approaches have …

Background The epidemiological, prognostic, and therapeutic features of child and
adolescent meningioma are poorly defined. Clinical knowledge has been drawn from small …

Meningiomas in children are poorly understood because they are rare. Recent reports have
provided a more complete description of their incidence, genetics, imaging features, and …

Epigenetic patterns on the level of DNA methylation have already been shown to separate
clinically relevant subgroups of meningiomas. We here set out to identify potential …