[HTML][HTML] Recent advances in mass spectrometry based clinical proteomics: applications to cancer research

A Macklin, S Khan, T Kislinger - Clinical proteomics, 2020 - Springer
Cancer biomarkers have transformed current practices in the oncology clinic. Continued
discovery and validation are crucial for improving early diagnosis, risk stratification, and …

Clinical applications of mass spectrometry‐based proteomics in cancer: Where are we?

EL Boys, J Liu, PJ Robinson, RR Reddel - Proteomics, 2023 - Wiley Online Library
Tumor tissue processing methodologies in combination with data‐independent acquisition
mass spectrometry (DIA‐MS) have emerged that can comprehensively analyze the …

The evolving role of mass spectrometry in cancer biomarker discovery

P Wang, JR Whiteaker, AG Paulovich - Cancer biology & therapy, 2009 - Taylor & Francis
Although the field of mass spectrometry-based proteomics is still in its infancy, recent
developments in targeted proteomic techniques have left the field poised to impact the …

Proteomics-driven cancer biomarker discovery: looking to the future

RJ Simpson, OK Bernhard, DW Greening… - Current opinion in …, 2008 - Elsevier
Availability of a suite of biomarkers for early detection, stratification into distinct subtypes,
and monitoring progression or response to therapy promises significant improvements in …

[HTML][HTML] Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

AG Birhanu - Clinical Proteomics, 2023 - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …

Clinical potential of mass spectrometry-based proteogenomics

B Zhang, JR Whiteaker, AN Hoofnagle… - Nature Reviews …, 2019 - nature.com
Cancer genomics research aims to advance personalized oncology by finding and targeting
specific genetic alterations associated with cancers. In genome-driven oncology, treatments …

Cancer proteomics

HT Tan, YH Lee, MCM Chung - Mass spectrometry reviews, 2012 - Wiley Online Library
Cancer presents high mortality and morbidity globally, largely due to its complex and
heterogenous nature, and lack of biomarkers for early diagnosis. A proteomics study of …

[HTML][HTML] Mass spectrometry for translational proteomics: progress and clinical implications

ES Baker, T Liu, VA Petyuk, KE Burnum-Johnson… - Genome medicine, 2012 - Springer
The utility of mass spectrometry (MS)-based proteomic analyses and their clinical
applications have been increasingly recognized over the past decade due to their high …

Mass spectrometry in clinical proteomics–from the present to the future

M Palmblad, A Tiss, R Cramer - PROTEOMICS–Clinical …, 2009 - Wiley Online Library
MS is an important analytical tool in clinical proteomics, primarily in the disease‐specific
discovery, identification and characterisation of proteomic biomarkers and patterns. MS …

[HTML][HTML] Mass spectrometry-assisted gel-based proteomics in cancer biomarker discovery: approaches and application

R Huang, Z Chen, L He, N He, Z Xi, Z Li, Y Deng… - Theranostics, 2017 - ncbi.nlm.nih.gov
There is a critical need for the discovery of novel biomarkers for early detection and targeted
therapy of cancer, a major cause of deaths worldwide. In this respect, proteomic …