Pain‐related increase in serotonin transporter gene methylation associates with emotional regulation in 4.5‐year‐old preterm‐born children

L Provenzi, M Fumagalli, G Scotto di Minico… - Acta …, 2020 - Wiley Online Library
Aim The main goal of this study was to assess the association between pain‐related
increase in serotonin transporter gene (SLC6A4) methylation and emotional dysregulation …

[HTML][HTML] Maternal sensitivity buffers the association between SLC6A4 methylation and socio-emotional stress response in 3-month-old full term, but not very preterm …

L Provenzi, M Fumagalli, R Giorda, F Morandi… - Frontiers in …, 2017 - frontiersin.org
Background Very preterm (VPT) infants are hospitalized in Neonatal Intensive Care Units
(NICUs) and are exposed to life-saving procedures eliciting pain-related stress. Recent …

[HTML][HTML] Pain-related stress during the Neonatal Intensive Care Unit stay and SLC6A4 methylation in very preterm infants

L Provenzi, M Fumagalli, I Sirgiovanni… - Frontiers in behavioral …, 2015 - frontiersin.org
Very preterm (VPT) infants need long-lasting hospitalization in the Neonatal Intensive Care
Unit (NICU) during which they are daily exposed to pain-related stress. Alterations of DNA …

Serotonin Transporter Gene (SLC6A4) Methylation Associates With Neonatal Intensive Care Unit Stay and 3‐Month‐Old Temperament in Preterm Infants

R Montirosso, L Provenzi, M Fumagalli… - Child …, 2016 - Wiley Online Library
Preterm birth and Neonatal Intensive Care Unit (NICU) stay are early adverse stressful
experiences, which may result in an altered temperamental profile. The serotonin transporter …

[HTML][HTML] Neonatal pain and COMT Val158Met genotype in relation to serotonin transporter (SLC6A4) promoter methylation in very preterm children at school age

CMY Chau, M Ranger, D Sulistyoningrum… - Frontiers in behavioral …, 2014 - frontiersin.org
Children born very preterm are exposed to repeated neonatal procedures that induce pain
and stress during hospitalization in the neonatal intensive care unit (NICU). The COMT …

SLC6A4 Promoter Region Methylation and Socio-Emotional Stress Response in Very Preterm and Full-Term Infants

R Montirosso, L Provenzi, R Giorda, M Fumagalli… - …, 2016 - Taylor & Francis
Aim: The present study is part of a prospective micro-longitudinal research project and
reports on the association between SLC6A4 methylation and socio-emotional stress …

The role of maternal touch in the association between SLC6A4 methylation and stress response in very preterm infants

ILC Mariani Wigley, E Mascheroni… - Developmental …, 2021 - Wiley Online Library
Very preterm (VPT) infants requiring hospitalization in the Neonatal Intensive Care Unit
(NICU) are exposed to several stressful procedural experiences. One consequence of NICU …

Adverse life events and allele-specific methylation of the serotonin transporter gene (SLC6A4) in adolescents: the TRAILS study

LJ van der Knaap, H Riese, JJ Hudziak… - Psychosomatic …, 2015 - journals.lww.com
Objectives Adverse life events increase vulnerability to affective disorders later in life,
possibly mediated by methylation of the serotonin transporter gene (SLC6A4). We …

[HTML][HTML] New-born females show higher stress- and genotype-independent methylation of SLC6A4 than males

H Dukal, J Frank, M Lang, J Treutlein, M Gilles… - … personality disorder and …, 2015 - Springer
Background Research has demonstrated an association between exposure to early life
stress and an increased risk of psychiatric disorders in later life, in particular depression …

[HTML][HTML] From early stress to 12-month development in very preterm infants: Preliminary findings on epigenetic mechanisms and brain growth

M Fumagalli, L Provenzi, P De Carli, F Dessimone… - PloS one, 2018 - journals.plos.org
Very preterm (VPT) infants admitted to Neonatal Intensive Care Unit (NICU) are at risk for
altered brain growth and less-than-optimal socio-emotional development. Recent research …