Adipose tissues are present at multiple locations in the body. Most blood vessels are
surrounded with adipose tissue which is referred to as perivascular adipose tissue (PVAT) …

The perivascular adipose tissue (PVAT) is now recognized as an active contributor to
vascular function. Adipocytes and stromal cells contained within PVAT are a source of an …

Significance: Perivascular adipose tissue (PVAT), which is present surrounding most blood
vessels, from the aorta to the microvasculature of the dermis, is mainly composed of fat cells …

Crosstalk between cells in the blood vessel wall is vital to normal vascular function and is
perturbed in diseases such as atherosclerosis and hypertension. Perivascular adipocytes …

Since the “rediscovery” of brown adipose tissue in adult humans, significant scientific efforts
are being pursued to identify the molecular mechanisms to promote a phenotypic change of …

Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …

Obesity is associated with increased risk of premature death, morbidity, and mortality from
several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD) …

Obesity is a leading risk factor for the development of type 2 diabetes mellitus (DM2) and
cardiovascular disease (CVD), however the underlying mechanisms still remain to be fully …

Perivascular adipose tissue (PVAT) surrounds most large blood vessels and plays an
important role in vascular homeostasis. PVAT releases various chemokines and …

Although adipocytes in PVAT can be classified into traditional white and brown adipocytes,
evidence suggests that PVAT adipocytes do not share the same developmental origin as …