We study the genotype-phenotype maps of 80 quantitative phenotypes in the model plant
Arabidopsis thaliana, by representing the genotypes affecting each phenotype as a …

The problem of missing heritability requires the consideration of genetic interactions among
different loci, called epistasis. Current GWAS statistical models require years to assess the …

A major challenge in evolutionary biology and plant breeding is to identify the genetic basis
of complex quantitative traits, including those that contribute to adaptive variation. Here we …

Highlights•We highlight recent advances in methods to predict genomic fitness variation
maps.•Fitness consequence maps help target functional coding and noncoding …

One of the main outcomes of quantitative genetics approaches to natural variation is to
reveal the genetic architecture underlying the phenotypic space. Complex genetic …

We resequenced 876 short fragments in a sample of 96 individuals of Arabidopsis thaliana
that included stock center accessions as well as a hierarchical sample from natural …

Arabidopsis thaliana is an important model organism for understanding the genetics and
molecular biology of plants. Its highly selfing nature, small size, short generation time, small …

Background Expression traits can vary quantitatively between individuals and have a
complex inheritance. Identification of the genetics underlying transcript variation can help in …

Quantitative traits in plants are controlled by a large number of genes and their interaction
with the environment. To disentangle the genetic architecture of such traits, natural variation …

Studying the genetic regulation of expression variation is a key method to dissect complex
phenotypic traits. To examine the genetic architecture of regulatory variation in Arabidopsis …