Autophagy, defined as a scavenging process of protein aggregates and damaged
organelles mediated by lysosomes, plays a significant role in the quality control of …

Macroautophagy (hereafter autophagy) is a lysosomal catabolic pathway that controls
cellular homeostasis and survival. It has recently emerged as an attractive target for the …

Autophagy is the major intracellular degradation system, by which cytoplasmic materials are
delivered to and degraded in the lysosome. As a quality control mechanism for cytoplasmic …

Autophagy, an evolutionarily conserved catabolic process involving the engulfment and
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …

Autophagy is a lysosome-dependent mechanism of intracellular degradation. The cellular
and molecular mechanisms underlying this process are highly complex and involve multiple …

Autophagy, a process of self-digestion of the cytoplasm and organelles through which
cellular components are recycled for reuse or energy production, is an evolutionarily …

Autophagy is a catabolic program that is responsible for the degradation of dysfunctional or
unnecessary proteins and organelles to maintain cellular homeostasis. Mechanistically, it …

Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …

Autophagy is central to the maintenance of organismal homeostasis in both physiological
and pathological situations. Accordingly, alterations in autophagy have been linked to …

Autophagy modulation is considered to be a promising programmed cell death mechanism
to prevent and cure a great number of disorders and diseases. The crucial step in designing …