Abstract In sub-Saharan Africa (SSA), the burden of noncommunicable diseases (NCDs) is
rising disproportionately in comparison to the rest of the world, affecting urban, semi-urban …

Congestive heart failure is a major problem in developed and developing countries alike.
Primary dysfunction of the heart muscle accounts for a significant proportion of patients with …

Cardiomyopathies are a heterogeneous group of cardiac muscle disorders that result in
dilated, hypertrophic, or restrictive pathophysiological entities. Dilated cardiomyopathy …

Background Cardiomyopathies are an important cause of heart failure in Africa yet there are
limited data on etiology and clinical phenotypes. Objectives The IMHOTEP (African …

Inherited cardiomyopathies include hypertrophic cardiomyopathy, dilated cardiomyopathy,
arrhythmogenic right ventricular cardiomyopathy, left ventricular noncompaction, and …

Background Cardiomyopathies affect more than 0.5% of the general population. They are
associated with high risk of sudden cardiac death, which can result from either heart failure …

Cardiomyopathy is defined as the weakening of the heart muscle, which reduces the ability
of the heart to pump blood. Inherited cardiomyopathies include hypertrophic, dilated …

unlike other parts of the world in which cardiomyopathy is rare, heart muscle disease is
endemic in Africa. The major forms of cardiomyopathy in Africa are dilated cardiomyopathy …

Research into the genetic aetiology of cardiomyopathies, and the clinical applications that
derive from this, has entered an exciting but highly challenging new phase in recent years …

Cardiovascular disease (CVD) is the leading cause of mortality globally. CVD comprises a
wide range of clinical entities, ie cardiomyopathies, hypertension, aortopathies, coronary …