Hemodynamic effects of pulsatile unloading of left ventricular assist devices (LVAD) on intraventricular flow and ventricular stress

K Gu, Z Guan, Y Chang, B Gao, Y Ling, Z Song… - Journal of …, 2020 - Elsevier
The role of pulsatile unloading in hemodynamic changes in intraventricular flow and
ventricular wall stress remains unknown. In this study, a finite element model of the left …

In Vitro Investigation of the Effect of Left Ventricular Assist Device Speed and Pulsatility Mode on Intraventricular Hemodynamics

F Chassagne, M Miramontes, VK Chivukula… - Annals of Biomedical …, 2021 - Springer
Stroke has become the main cause of mortality and morbidity in patients treated with Left
Ventricular Assist Devices (LVADs). The hemodynamics of the left ventricle are altered by …

Effect of counter-pulsation control of a pulsatile left ventricular assist device on working load variations of the native heart

SW Choi, KW Nam, KM Lim, EB Shim, YS Won… - Biomedical engineering …, 2014 - Springer
Background When using a pulsatile left ventricular assist device (LVAD), it is important to
reduce the cardiac load variations of the native heart because severe cardiac load variations …

Superior performance of continuous over pulsatile flow ventricular assist devices in the single ventricle circulation: A computational study

T Schmidt, D Rosenthal, O Reinhartz, K Riemer… - Journal of …, 2017 - Elsevier
This study compares the physiological responses of systemic-to-pulmonary shunted single
ventricle patients to pulsatile and continuous flow ventricular assist devices (VADs) …

Continuous flow left ventricular pump support and its effect on regional left ventricular wall stress: finite element analysis study

CS Jhun, K Sun, JP Cysyk - Medical & biological engineering & computing, 2014 - Springer
Left ventricular assist device (LVAD) support unloads left ventricular (LV) pressure and
volume and decreases wall stress. This study investigated the effect of systematic LVAD …

The influence of different operating conditions on the blood damage of a pulsatile ventricular assist device

Z Xu, M Yang, X Wang, Z Wang - ASAIO Journal, 2015 - journals.lww.com
Because of pulsatile blood flow's benefit for myocardial recovery, perfusion of coronary
arteries and end organs, pulsatile ventricular assist devices (VADs) are still widely used as …

Salutary effects of the PULVAD, a novel implantable counterpulsation assist device, on cardiac mechanoenergetics

C Kontogiannis, D Aravantinos, I Nanas… - ASAIO …, 2019 - journals.lww.com
Abstract The Pressure Unloading Left Ventricular Assist Vevice (PULVAD) is a novel
implantable counterpulsation LVAD, designed to provide ventricular unloading with …

Investigating the role of interventricular interdependence in development of right heart dysfunction during LVAD support: a patient-specific methods-based approach

KL Sack, Y Dabiri, T Franz, SD Solomon… - Frontiers in …, 2018 - frontiersin.org
Predictive computation models offer the potential to uncover the mechanisms of treatments
whose actions cannot be easily determined by experimental or imaging techniques. This is …

Left ventricular pressure and volume unloading during pulsatile versus nonpulsatile left ventricular assist device support

S Klotz, MC Deng, J Stypmann, J Roetker… - The Annals of thoracic …, 2004 - Elsevier
BACKGROUND: Nonpulsatile axial or centrifugal pumps are the latest generation of left
ventricular assist devices (LVAD). Whether left ventricular (LV) unloading and outcome in …

The effect of heart failure and left ventricular assist device treatment on right ventricular mechanics: a computational study

JIK Park, AK Heikhmakhtiar, CH Kim, YS Kim… - BioMedical Engineering …, 2018 - Springer
Background and aims Although it is important to analyze the hemodynamic factors related to
the right ventricle (RV) after left ventricular assist device (LVAD) implantation, previous …