Infertility has become a major social concern, with high demand for treatment. Due to the
high prevalence of genetic abnormalities among men suffering from infertility with severe …

Male infertility is a common problem. There is growing evidence that infertile men may
harbor significant illness and disease. Many of the genetic causes of male fertility have …

Genetic causes can be directly responsible for various clinical conditions of male infertility
and spermatogenic impairment. With the increased use of assisted reproduction …

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Abstract Infertility affects 8%–12% of couples worldwide with a male factor contributing to
nearly 50% of couples either as a primary or contributing cause. Several genetic factors that …

Purpose This review provides an update on the genetics of male infertility with emphasis on
the current state of research, the genetic disorders that can lead to non-syndromic male …

Infertility is a major health problem which affects approximately 22% of married couples in
reproductive age. The apparent increased incidence of male infertility, in parallel with the …

Male infertility is an extraordinarily common problem affecting 1 in 25 men. Despite active
research, the underlying causal factors remain unknown in a large percentage (40%) of …

While 7% of the men are infertile, currently, a genetic etiology is identified in less than 25%
of those men, and 30% of the infertile men lack a definitive diagnosis, falling in the …

Introduction Thousands of genes are implicated in spermatogenesis, testicular development
and endocrine regulation of testicular function. The genetic contribution to male infertility is …