[HTML][HTML] 5,10‑Methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms in patients with nonsyndromic cleft lip and palate

Y Komiyama, C Koshiji… - Biomedical …, 2020 - … .spandidos-publications.com
Cleft lip with or without cleft palate (CL/P) is considered a multifactorial genetic disorder.
Folic acid metabolism has been suggested to underlie the development of CL/P. The gene …

Family-based association study of the MTHFR polymorphism C677T in patients with nonsyndromic cleft lip and palate from central Europe

H Reutter, S Birnbaum, AD Lacava… - The Cleft palate …, 2008 - journals.sagepub.com
Objective: The 677C→ T allele in the 5, 10-methylenetetrahydrofolate reductase (MTHFR)
gene has been implicated in the etiology of nonsyndromic cleft lip and palate (CL/P). This …

Determination of Methylenetetrahydrofolate Reductase (MTHFR) gene polymorphism in Turkish patients with nonsyndromic cleft lip and palate

D Aşlar, E Özdiler, AT Altuğ, H Taştan - International journal of pediatric …, 2013 - Elsevier
OBJECTIVE: To investigate the association between MTHFR C677T polymorphism and
Turkish patients with nonsyndromic cleft lip and/or palate (nsCL/P) and to determine the …

The common MTHFR C677T and A1298C variants are not associated with the risk of non-syndromic cleft lip/palate in northern Venezuela

MA Sözen, MM Tolarova, RA Spritz - Journal of Genetics and Genomics, 2009 - Elsevier
Non-syndromic cleft lip with or without cleft palate (nsCL/P) is among the most common
major birth defects, with complex inheritance involving multiple genes and environmental …

Association of methylenetetrahydrofolate reductase A1298C polymorphisms with non-syndromic cleft lip with or without cleft palate

Y Hu, W Hou, EJ Chen, XH Liu, CL Hou… - … kou Qiang yi xue za zhi …, 2011 - europepmc.org
Objective To investigate the association between a polymorphism of
methylenetetrahydrofolate reductase with Non-syndromic cleft lip with or without cleft palate …

Association between C677T and A1298C MTHFR gene polymorphism and nonsyndromic orofacial clefts in the Turkish population: a case-parent study

A Semiç-Jusufagiç, R Bircan, Ö Çelebiler… - The Turkish Journal …, 2012 - turkjpediatr.org
Two common MTHFR gene polymorphisms (C677T and A1298C) have been implicated in
the etiology of nonsyndromic cleft lip/palate (nsCL/P). To investigate the genotype …

Relationship between nonsyndromic cleft lip with or without cleft palate (NSCL/P) and genetic polymorphisms of MTHFR C677T and A1298C

WD Wan, LJ Wang, XP Zhou, DL Zhou… - … Zheng Xing Wai Ke …, 2006 - europepmc.org
Objective To explore the relationship between nonsyndromic cleft lip with or without cleft
palate (NSCL/P) and genetic polymorphism of MTHFR C677T and A1298C in Chinese …

Relationship between genetic polymorphisms of MTHFR C677T and nonsyndromic cleft lip with or without palate

JZ Guo, XM Song, Y Wang, WL Zhu… - … da xue xue bao. Yi xue …, 2009 - europepmc.org
Objective To explore the relationship between genetic polymorphisms of MTHFR C677T and
nonsyndromic cleft lip with or without palate in Chinese population. Methods There were 97 …

Single-nucleotide polymorphisms of methylenetetrahydrofolate reductase gene in a South Indian cohort with nonsyndromic cleft lip with or without palate

R Abdulla, J Kudkuli, S Kapoor, V Prabhu… - Journal of Oral and …, 2020 - journals.lww.com
Objective: Clefts of the lip, with or without cleft palate and cleft palate only, collectively called
as orofacial clefts (OFCs) are one of the most common congenital malformations with …

MTHFR C677T polymorphism and risk of nonsyndromic cleft lip with or without cleft palate in the Moroccan population

A Rafik, L Rachad, A Kone, S Nadifi - The Application of Clinical …, 2019 - Taylor & Francis
Background Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most
common craniofacial malformations observed. Several studies suggest that the decrease in …