Dynamic control of the high-affinity iron uptake complex in root epidermal cells

A Martín-Barranco, J Spielmann, G Dubeaux… - Plant …, 2020 - academic.oup.com
In plants, iron uptake from the soil is tightly regulated to ensure optimal growth and
development. Iron absorption in Arabidopsis root epidermal cells requires the IRT1 …

Monoubiquitin-dependent endocytosis of the iron-regulated transporter 1 (IRT1) transporter controls iron uptake in plants

M Barberon, E Zelazny, S Robert… - Proceedings of the …, 2011 - National Acad Sciences
Plants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1)
high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow …

Arabidopsis IRT2 cooperates with the high-affinity iron uptake system to maintain iron homeostasis in root epidermal cells

G Vert, M Barberon, E Zelazny, M Séguéla, JF Briat… - Planta, 2009 - Springer
Iron is an essential nutrient for all organisms but toxic when present in excess.
Consequently, plants carefully regulate their iron uptake, dependent on the FRO2 ferric …

Differential metal sensing and metal‐dependent degradation of the broad spectrum root metal transporter IRT1

J Spielmann, V Cointry, F Devime, S Ravanel… - The Plant …, 2022 - Wiley Online Library
Iron is an essential micronutrient for plant growth and development. Under low iron
conditions, Arabidopsis plants take up soil iron using the root iron transporter IRT1. In …

Metal sensing by the IRT1 transporter-receptor orchestrates its own degradation and plant metal nutrition

G Dubeaux, J Neveu, E Zelazny, G Vert - Molecular cell, 2018 - cell.com
Plant roots forage the soil for iron, the concentration of which can be dramatically lower than
those needed for growth. Soil iron uptake uses the broad metal spectrum IRT1 transporter …

Polarization of IRON-REGULATED TRANSPORTER 1 (IRT1) to the plant-soil interface plays crucial role in metal homeostasis

M Barberon, G Dubeaux, C Kolb… - Proceedings of the …, 2014 - National Acad Sciences
In plants, the controlled absorption of soil nutrients by root epidermal cells is critical for
growth and development. IRON-REGULATED TRANSPORTER 1 (IRT1) is the main root …

Root‐to‐shoot iron partitioning in Arabidopsis requires IRON‐REGULATED TRANSPORTER1 (IRT1) protein but not its iron (II) transport function

J Quintana, M Bernal, M Scholle… - The Plant …, 2022 - Wiley Online Library
SUMMARY IRON‐REGULATED TRANSPORTER1 (IRT1) is the root high‐affinity ferrous
iron (Fe) uptake system and indispensable for the completion of the life cycle of Arabidopsis …

IRT1 DEGRADATION FACTOR1, a RING E3 Ubiquitin Ligase, Regulates the Degradation of IRON-REGULATED TRANSPORTER1 in Arabidopsis

LJ Shin, JC Lo, GH Chen, J Callis, H Fu… - The Plant Cell, 2013 - academic.oup.com
Fe is an essential micronutrient for plant growth and development; plants have developed
sophisticated strategies to acquire ferric Fe from the soil. Nongraminaceous plants acquire …

Expression of the IRT1 metal transporter is controlled by metals at the levels of transcript and protein accumulation

EL Connolly, JP Fett, ML Guerinot - The Plant Cell, 2002 - academic.oup.com
Iron, an essential nutrient, is not readily available to plants because of its low solubility. In
addition, iron is toxic in excess, catalyzing the formation of hydroxyl radicals that can …

Iron-induced turnover of the Arabidopsis IRON-REGULATED TRANSPORTER1 metal transporter requires lysine residues

L Kerkeb, I Mukherjee, I Chatterjee, B Lahner… - Plant …, 2008 - academic.oup.com
Iron is an essential micronutrient but is toxic if accumulated at high levels. Thus, iron uptake
and distribution in plants are controlled by precise regulatory mechanisms. IRON …