Epigenetic alterations and advancement of treatment in peripheral T-cell lymphoma

P Zhang, M Zhang - Clinical epigenetics, 2020 - Springer
Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of clinically
aggressive diseases associated with poor prognosis. Except for ALK+ anaplastic large-cell …

[HTML][HTML] Histone modifier gene mutations in peripheral T-cell lymphoma not otherwise specified

MM Ji, YH Huang, JY Huang, ZF Wang, D Fu… - …, 2018 - ncbi.nlm.nih.gov
Due to heterogeneous morphological and immunophenotypic features, approximately 50%
of peripheral T-cell lymphomas are unclassifiable and categorized as peripheral T-cell …

Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma

TB Heavican, A Bouska, J Yu, W Lone… - Blood, The Journal …, 2019 - ashpublications.org
Peripheral T-cell lymphoma (PTCL) is a group of complex clinicopathological entities, often
associated with an aggressive clinical course. Angioimmunoblastic T-cell lymphoma (AITL) …

Molecular and genomic landscape of peripheral T-cell lymphoma

J Iqbal, C Amador, TW McKeithan, WC Chan - T-Cell and NK-Cell …, 2019 - Springer
Peripheral T-cell lymphoma (PTCL) is an uncommon group of lymphoma covering a diverse
spectrum of entities. Little was known regarding the molecular and genomic landscapes of …

Correlation of mutational landscape and survival outcome of peripheral T-cell lymphomas

Y Ye, N Ding, L Mi, Y Shi, W Liu, Y Song, S Shu… - … hematology & oncology, 2021 - Springer
Objective To explore the correlation of mutation landscape with clinical outcomes in patients
with peripheral T-cell lymphoma (PTCL). Methods We retrospectively analyzed the …

Pathology of peripheral T-cell lymphomas: where do we stand?

P Gaulard, L de Leval - Seminars in hematology, 2014 - Elsevier
Peripheral T-cell lymphomas (PTCLs) are heterogeneous and uncommon malignancies
characterized by a usually aggressive clinical course. The current World Health …

New molecular insights into peripheral T cell lymphomas

SA Pileri, PP Piccaluga - The Journal of clinical …, 2012 - Am Soc Clin Investig
Peripheral T cell lymphomas (PTCLs) are heterogeneous neoplasms and represent about
12% of all lymphoid malignancies. They are often regarded as “orphan diseases,” a …

Combined oral 5-azacytidine and romidepsin are highly effective in patients with PTCL: a multicenter phase 2 study

L Falchi, H Ma, S Klein, JK Lue… - Blood, The Journal …, 2021 - ashpublications.org
Peripheral T-cell lymphomas (PTCLs) are uniquely vulnerable to epigenetic modifiers. We
demonstrated in vitro synergism between histone deacetylase inhibitors and DNA …

Peripheral T-cell lymphoma

FM Foss, PL Zinzani, JM Vose… - Blood, The Journal …, 2011 - ashpublications.org
Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of clinically aggressive
diseases associated with poor outcome. Studies that focus specifically on PTCL are …

Genetic landscape and classification of peripheral T cell lymphomas

RF Sandell, RL Boddicker, AL Feldman - Current oncology reports, 2017 - Springer
Purpose of review Peripheral T cell lymphomas (PTCLs) are markedly heterogeneous at the
clinical, pathological, and molecular levels. This review will discuss genetic findings in PTCL …