Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease

MS Uddin, MT Kabir, D Tewari, B Mathew… - Science of the Total …, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive, chronic and severe neurodegenerative disorder
linked with cognitive and memory impairment that eventually lead to death. There are …

Protective effects of flavonoids against Alzheimer's disease: pathological hypothesis, potential targets, and structure–activity relationship

J Li, M Sun, X Cui, C Li - International Journal of Molecular Sciences, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease with high morbidity and mortality,
for which there is no available cure. Currently, it is generally believed that AD is a disease …

Molecular insight into the therapeutic promise of flavonoids against Alzheimer's disease

MS Uddin, MT Kabir, K Niaz, P Jeandet, C Clément… - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is one of the utmost chronic neurodegenerative disorders, which is
characterized from a neuropathological point of view by the aggregates of amyloid beta (Aβ) …

Biflavonoids as potential small molecule therapeutics for Alzheimer's disease

A Thapa, EY Chi - Natural compounds as therapeutic agents for …, 2015 - Springer
Flavonoids are naturally occurring phytochemicals found in a variety of fruits and vegetables
and offer color, flavor, aroma, nutritional and health benefits. Flavonoids have been found to …

Flavonoids as promising neuroprotectants and their therapeutic potential against Alzheimer's disease

T Minocha, H Birla, AA Obaid, V Rai… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is one of the serious and progressive neurodegenerative
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …

Flavonoids as therapeutic compounds targeting key proteins involved in Alzheimer's disease

FI Baptista, AG Henriques, AMS Silva… - ACS chemical …, 2014 - ACS Publications
Alzheimer's disease is characterized by pathological aggregation of protein tau and amyloid-
β peptides, both of which are considered to be toxic to neurons. Naturally occurring dietary …

Flavonoids with potential anti-amyloidogenic effects as therapeutic drugs for treating Alzheimer's disease

Q Wang, X Dong, R Zhang… - Journal of Alzheimer's …, 2021 - content.iospress.com
Alzheimer's disease (AD) is a central neurodegenerative disease generally among the
elderly; it accounts for approximately 50–75% of total cases of dementia patients and poses …

The neuroprotective potentiality of flavonoids on Alzheimer's disease

A Calderaro, GT Patanè, E Tellone, D Barreca… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), due to its spread, has become a global health priority, and is
characterized by senile dementia and progressive disability. The main cause of AD and …

[PDF][PDF] The role of natural flavonoids on neuroinflammation as a therapeutic target for Alzheimer's disease: a narrative review

Q Zhang, Y Yan - Neural Regeneration Research, 2023 - journals.lww.com
Alzheimer's disease is a neurodegenerative disease that affects a large proportion of older
adult people and is characterized by memory loss, progressive cognitive impairment, and …

[HTML][HTML] Potential of flavonoids as anti-Alzheimer's agents: Bench to bedside

R Kaur, A Sood, DK Lang, S Bhatia… - … Science and Pollution …, 2022 - Springer
Developing therapies for neurodegenerative diseases are challenging because of the
presence of blood–brain barrier and Alzheimer being one of the commonest and uprising …