One of the concepts explaining the coincidence of obesity and type 2 diabetes (T2D) is the
metaflammation theory. This chronic, low-grade inflammatory state originating from …

Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation,
recently referred to as 'metaflammation', a relevant factor contributing to the development of …

The association between the metabolic syndrome and a pathological activation of the innate
immune system is now well established. Thus, defective insulin secretion and action are …

The research in the past decades has revealed a critical link between metabolic disorders
and inflammation, which leads to a concept called “metaflammation.” Metaflammation is a …

The modern rise in obesity and its strong association with insulin resistance and type 2
diabetes have elicited interest in the underlying mechanisms of these pathologies. The …

Recent studies have shown that immune system cells take an active part in the regulation of
metabolic homeostasis. Disruption of the interaction between the immune system and …

Obesity is a major risk factor for type 2 diabetes mellitus (T2DM), which is a significant health
problem worldwide. Active disease is associated with low-grade chronic inflammation …

It is recognized that a chronic low-grade inflammation and an activation of the immune
system are involved in the pathogenesis of obesity-related insulin resistance and type 2 …

Introduction: There is a growing body of evidence to suggest that chronic silent inflammation
is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and …

AIM: The aim of this paper is to provide the fundamental background of the inflammation
theory associated with type 2 diabetes, to discuss the clinical consequences of low-grade …