[HTML][HTML] Therapeutically significant microRNAs in primary and metastatic brain malignancies

AA Balachandran, LM Larcher, S Chen, RN Veedu - Cancers, 2020 - mdpi.com
Simple Summary The overall survival of brain cancer patients remains grim, with
conventional therapies such as chemotherapy and radiotherapy only providing marginal …

[HTML][HTML] Exploring the role of microRNAs in glioma progression, prognosis, and therapeutic strategies

O Tluli, M Al-Maadhadi, AA Al-Khulaifi, AF Akomolafe… - Cancers, 2023 - mdpi.com
Simple Summary Despite advancements in healthcare and research, the occurrence of
gliomas, a type of brain tumor, continues to rise. Emerging evidence has proven that …

[HTML][HTML] Role of microRNAs in glioblastoma

M Chen, Z Medarova, A Moore - Oncotarget, 2021 - ncbi.nlm.nih.gov
Glioblastoma is the most common and aggressive primary human brain cancer. MicroRNAs
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …

MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics

A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

MicroRNAs in human malignant gliomas

M Mizoguchi, Y Guan, K Yoshimoto, N Hata… - Journal of …, 2012 - Wiley Online Library
MicroRNA (miRNA) is a new class of small noncoding RNA molecules that regulate a wide
spectrum of gene expression in a posttranscriptional manner. MiRNAs play crucial roles in …

[PDF][PDF] MicroRNAs in glioblastoma multiforme: profiling studies and therapeutic impacts

DG LeBrun, M Li - Molecular and Cellular Pharmacology, 2011 - mcpharmacol.com
Glioblastoma multiforme (GBM) is the most lethal primary brain tumor and is characterized
by a poor prognosis, resistance to standard therapies, and a highly mutated tumor genome …

[PDF][PDF] MicroRNAs in human glioblastoma: from bench to beside

H Wang, T Xu, Y Jiang, Y Yan, R Qin… - Front Biosci (Landmark …, 2015 - researchgate.net
Glioblastoma (GBM) is the most common and malignant adult primary brain tumor and one
of the most lethal types of all cancers. Currently, despite interventional therapy (eg …

[HTML][HTML] MicroRNA in human glioma

M Li, J Li, L Liu, W Li, Y Yang, J Yuan - Cancers, 2013 - mdpi.com
Glioma represents a serious health problem worldwide. Despite advances in surgery,
radiotherapy, chemotherapy, and targeting therapy, the disease remains one of the most …

miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay

SS Elshaer, AI Abulsoud, D Fathi… - … -Research and Practice, 2023 - Elsevier
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy

A Nikaki, C Piperi, AG Papavassiliou - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Gliomas consist of a very heterogeneous group of malignant tumors,
accounting for 50–60% of primary brain tumors. Despite all the efforts of cytoreductive …