Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

Brain metastases are a serious obstacle in the treatment of patients with solid tumors and
contribute to the morbidity and mortality of these cancers. It is speculated that the frequency …

An estimated 20% of all patients with cancer will develop brain metastases, with the majority
of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma …

Metastatic tumours involving the brain overshadow primary brain neoplasms in frequency
and are an important complication in the overall management of many cancers. Importantly …

Brain metastases (BM) are the most common intracranial neoplasm in adults. Initially
considered as an essentially terminal stage of advanced cancer, BM are increasingly being …

Many patients with lung cancer, breast cancer, and melanoma develop brain metastases
that are resistant to conventional therapy. The median survival for untreated patients is 1 to 2 …

Brain metastases are the most common intracranial tumors and their incidence is increasing.
Untreated brain metastases are associated with a poor prognosis and a poor performance …

Metastasizing cancer cells that arrest in brain microvessels have to face an organ
microenvironment that is alien, and exclusive. In order to survive and thrive in this foreign …

Brain metastasis, the secondary growth of malignant cells within the central nervous system
(CNS), exceeds the incidence of primary brain tumors (ie, gliomas) by tenfold and are …

Brain metastasis is a major public health problem. An alarming increase in the incidence of
brain metastasis in patients with otherwise well controlled systemic cancer has drawn …