Circulating tumor necrosis factor receptors: a potential biomarker for the progression of diabetic kidney disease

M Murakoshi, T Gohda, Y Suzuki - International journal of molecular …, 2020 - mdpi.com
Despite considerable advancements in medicine, the optimal treatment for chronic kidney
disease (CKD), especially diabetic kidney disease (DKD), remains a major challenge. More …

Circulating TNF receptors 1 and 2 predict progression of diabetic kidney disease: A meta‐analysis

X Ye, T Luo, K Wang, Y Wang, S Yang… - Diabetes/Metabolism …, 2019 - Wiley Online Library
Background We conducted a meta‐analysis to investigate the association of circulating
tumor necrosis factor‐1 (TNFR‐1) and TNFR‐2 with diabetic kidney disease (DKD) …

Novel biomarkers for the progression of diabetic nephropathy: soluble TNF receptors

T Gohda, Y Tomino - Current Diabetes Reports, 2013 - Springer
Despite 2 decades of advances in therapy of diabetic patients, the prevalence of diabetic
nephropathy among patients with diabetes has not decreased. However, large-scale …

The signaling pathway of TNF receptors: Linking animal models of renal disease to human CKD

I Lousa, F Reis, A Santos-Silva, L Belo - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) has been recognized as a global public health problem.
Despite the current advances in medicine, CKD-associated morbidity and mortality remain …

Circulating TNF receptors predict cardiovascular disease in patients with chronic kidney disease

E Bae, RH Cha, YC Kim, JN An, DK Kim, KD Yoo… - Medicine, 2017 - journals.lww.com
Cardiovascular disease (CVD) is the main public health problem in patients with chronic
kidney disease (CKD); however, there is no established biomarker for predicting CVD …

Circulating tumor necrosis factor-related biomarkers predict kidney function decline in Japanese patients with diabetes: An observational cohort study

M Murakoshi, N Kamei, Y Suzuki, M Kubota… - Diabetes Research and …, 2023 - Elsevier
Aims Tumor necrosis factor (TNF) receptors (TNFRs: TNFR1 and, TNFR2) are reportedly
associated with chronic kidney disease (CKD) progression chiefly in Caucasian patients …

The role of TNF-α in diabetic nephropathy: pathogenic and therapeutic implications

JF Navarro, C Mora-Fernández - Cytokine & growth factor reviews, 2006 - Elsevier
Diabetes mellitus and its complications are a public health problem. Diabetic nephropathy
has become the main cause of renal failure, and furthermore is associated with a dramatic …

Association between circulating tumor necrosis factor-related biomarkers and estimated glomerular filtration rate in type 2 diabetes

N Kamei, M Yamashita, Y Nishizaki, N Yanagisawa… - Scientific Reports, 2018 - nature.com
Chronic inflammation plays a crucial role in the development/progression of diabetic kidney
disease. The involvement of tumor necrosis factor (TNF)-related biomarkers [TNFα …

Tumor necrosis factor-α as a therapeutic target for diabetic nephropathy

JF Navarro-González, A Jarque, M Muros… - Cytokine & growth factor …, 2009 - Elsevier
Activation of innate immunity with the subsequent development of a chronic low-grade
inflammatory response is now recognized as a critical factor in the pathogenesis of diabetes …

A profile of multiple circulating tumor necrosis factor receptors associated with early progressive kidney decline in Type 1 Diabetes is similar to profiles in autoimmune …

K Ihara, J Skupien, B Krolewski, I Zaipul, K O'Neil… - Kidney International, 2021 - Elsevier
This study comprehensively evaluated the association between known circulating tumor
necrosis factor (TNF) superfamily ligands and receptors and the development of early …