FIT, a regulatory hub for iron deficiency and stress signaling in roots, and FIT-dependent and-independent gene signatures

B Schwarz, P Bauer - Journal of Experimental Botany, 2020 - academic.oup.com
Iron (Fe) is vital for plant growth. Plants balance the beneficial and toxic effects of this
micronutrient, and tightly control Fe uptake and allocation. Here, we review the role of the …

Iron homeostasis in Arabidopsis thaliana: transcriptomic analyses reveal novel FIT-regulated genes, iron deficiency marker genes and functional gene networks

HJ Mai, S Pateyron, P Bauer - BMC Plant Biology, 2016 - Springer
Abstract Background FIT (FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION
FACTOR) is the central regulator of iron uptake in Arabidopsis thaliana roots. We performed …

Proteasome‐mediated turnover of the transcriptional activator FIT is required for plant iron‐deficiency responses

A Sivitz, C Grinvalds, M Barberon, C Curie… - The Plant …, 2011 - Wiley Online Library
Plants display a number of responses to low iron availability in order to increase iron uptake
from the soil. In the model plant Arabidopsis thaliana, the ferric‐chelate reductase FRO2 and …

Posttranslational regulation of the iron deficiency basic helix-loop-helix transcription factor FIT is affected by iron and nitric oxide

J Meiser, S Lingam, P Bauer - Plant Physiology, 2011 - academic.oup.com
Understanding iron (Fe) sensing and regulation is important for targeting key genes for
important nutritional traits like Fe content. The basic helix-loop-helix transcription factor FIT …

Arabidopsis bHLH100 and bHLH101 control iron homeostasis via a FIT-independent pathway

AB Sivitz, V Hermand, C Curie, G Vert - 2012 - journals.plos.org
Iron deficiency induces a complex set of responses in plants, including developmental and
physiological changes, to increase iron uptake from soil. In Arabidopsis, many transporters …

bHLH121 functions as a direct link that facilitates the activation of FIT by bHLH IVc transcription factors for maintaining Fe homeostasis in Arabidopsis

R Lei, Y Li, Y Cai, C Li, M Pu, C Lu, Y Yang, G Liang - Molecular plant, 2020 - cell.com
Iron (Fe) deficiency is prevalent in plants grown in neutral or alkaline soil. Plants have
evolved sophisticated mechanisms that regulate Fe homeostasis, ensuring survival. In …

Understanding the complexity of iron sensing and signaling cascades in plants

T Kobayashi - Plant and Cell Physiology, 2019 - academic.oup.com
Under iron-deficient conditions, plants induce the expression of a set of genes involved in
iron uptake and translocation. This response to iron deficiency is regulated by transcriptional …

Zinc finger of Arabidopsis thaliana12 (ZAT12) interacts with FER-like iron deficiency-induced transcription factor (FIT) linking iron deficiency and oxidative stress …

CTT Le, T Brumbarova, R Ivanov, C Stoof… - Plant …, 2016 - academic.oup.com
Plants grown under iron (Fe)-deficient conditions induce a set of genes that enhance the
efficiency of Fe uptake by the roots. In Arabidopsis (Arabidopsis thaliana), the central …

All together now: regulation of the iron deficiency response

N Riaz, ML Guerinot - Journal of Experimental Botany, 2021 - academic.oup.com
Iron (Fe) is one of the essential micronutrients required by both plants and animals. In
humans, Fe deficiency causes anemia, the most prevalent nutritional disorder. Most people …

Local and systemic signaling of iron status and its interactions with homeostasis of other essential elements

SR Gayomba, Z Zhai, H Jung… - Frontiers in Plant …, 2015 - frontiersin.org
Iron (Fe) is essential for plant growth and development. However, alkaline soils, which
occupy approximately 30% of the world's arable lands, are considered Fe-limiting for plant …