[HTML][HTML] The sociability spectrum: evidence from reciprocal genetic copy number variations

A López-Tobón, S Trattaro, G Testa - Molecular Autism, 2020 - Springer
Sociability entails some of the most complex behaviors processed by the central nervous
system. It includes the detection, integration, and interpretation of social cues and …

[HTML][HTML] A self-generated environmental factor as a potential contributor to atypical early social communication in autism

T Kikusui, N Hiroi - Neuropsychopharmacology, 2017 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is defined by deficits in reciprocal social communication
and interactions, as well as deficits in cognitive and behavioral flexibility. In the United …

[HTML][HTML] Social Responsiveness Scale-aided analysis of the clinical impact of copy number variations in autism

E van Daalen, C Kemner, NE Verbeek… - Neurogenetics, 2011 - Springer
Recent array-based studies have detected a wealth of copy number variations (CNVs) in
patients with autism spectrum disorders (ASD). Since CNVs also occur in healthy …

Neural endophenotypes of social behavior in autism spectrum conditions

MV Lombardo, S Baron-Cohen, MK Belmonte… - 2011 - academic.oup.com
Autism is characterized by qualitative impairments in social interaction, communication, and
stereotyped repetitive behaviors and/or restricted interests. Beyond these diagnostic criteria …

[HTML][HTML] Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence

B St Pourcain, DH Skuse, WP Mandy, K Wang… - Molecular autism, 2014 - Springer
Background Social-communication abilities are heritable traits, and their impairments
overlap with the autism continuum. To characterise the genetic architecture of social …

Circuits underlying social function and dysfunction

Z Wang, H Yueh, M Chau… - Autism …, 2023 - Wiley Online Library
Substantial advances have been made toward understanding the genetic and
environmental risk factors for autism, a neurodevelopmental disorder with social impairment …

The emerging biology of autism spectrum disorders

MW State, N Šestan - Science, 2012 - science.org
Autism spectrum disorders (ASD) are a genetically and phenotypically heterogeneous group
of syndromes defined by fundamental impairments in social reciprocity and language …

Social behavior in 16p11. 2 and 22q11. 2 copy number variations: Insights from mice and humans

A Benedetti, C Molent, W Barcik… - Genes, Brain and …, 2022 - Wiley Online Library
Abstract Genetic 16p11. 2 and 22q11. 2 deletions and duplications in humans may alter
behavioral developmental trajectories increasing the risk of autism and schizophrenia …

Social responsiveness, an autism endophenotype: genomewide significant linkage to two regions on chromosome 8

JK Lowe, DM Werling, JN Constantino… - American Journal of …, 2015 - Am Psychiatric Assoc
Objective: Autism spectrum disorder is characterized by deficits in social function and the
presence of repetitive and restrictive behaviors. Following a previous test of principle, the …

Genetic architecture of reciprocal social behavior in toddlers: Implications for heterogeneity in the early origins of autism spectrum disorder

N Marrus, JD Grant, B Harris-Olenak… - Development and …, 2020 - cambridge.org
Impairment in reciprocal social behavior (RSB), an essential component of early social
competence, clinically defines autism spectrum disorder (ASD). However, the behavioral …