Frequency of first and second-line drug resistance-associated mutations among resistant Mycobacterium tuberculosis clinical isolates from São Paulo, Brazil

T Matsui, JMW Pinhata, MCS Rabello… - Memórias do Instituto …, 2020 - SciELO Brasil
BACKGROUND Tuberculosis (TB) is an infectious disease caused by the bacterium
Mycobacterium tuberculosis, and the number of new cases of multidrug resistant TB (MDR …

Multidrug Resistant Mycobacterium tuberculosis: A Retrospective katG and rpoB Mutation Profile Analysis in Isolates from a Reference Center in Brazil

FAD de Freitas, V Bernardo, MK Gomgnimbou, C Sola… - PloS one, 2014 - journals.plos.org
Background Multidrug resistance is a critical factor in tuberculosis control. To gain better
understanding of multidrug resistant tuberculosis in Brazil, a retrospective study was …

[HTML][HTML] Molecular characterization of mutations associated with resistance to second line drugs in Mycobacterium tuberculosis patients from Casablanca, Morocco

G Momen, A Aainouss, A Lamaammal… - Revista do Instituto de …, 2021 - SciELO Brasil
The emergence and spread of extensively drug-resistant tuberculosis (XDR-TB) is a serious
threat to global health. Therefore, its rapid diagnosis is crucial. The present study aimed to …

[HTML][HTML] Clinical data and molecular analysis of Mycobacterium tuberculosis isolates from drug-resistant tuberculosis patients in Goiás, Brazil

SLÁ Alves, FS Metzker, JA Araújo-Filho… - Memórias do Instituto …, 2011 - SciELO Brasil
Drug resistance is one of the major concerns regarding tuberculosis (TB) infection
worldwide because it hampers control of the disease. Understanding the underlying …

[HTML][HTML] Multidrug-resistant tuberculosis

ACM Lemos, ED Matos - The Brazilian Journal of Infectious Diseases, 2013 - Elsevier
Despite the efforts made worldwide to reduce the number of cases of drug-susceptible
tuberculosis, multidrug-resistant tuberculosis (MDR-TB) constitutes an important public …

Characteristics of multidrug-resistant Mycobacterium tuberculosis in southern Brazil

PF Perizzolo, ER Dalla Costa, AW Ribeiro, FS Spies… - Tuberculosis, 2012 - Elsevier
A major threat to tuberculosis (TB) control programs is the emergence of drug resistant
Mycobacterium tuberculosis strains that cause TB that cannot be cured by standard anti-TB …

A high prevalence of resistance in new tuberculosis cases of midwestern Brazil

LC Santos, H de Macedo Bousquet, AM Pereira… - Infection, Genetics and …, 2010 - Elsevier
Tuberculosis (TB) is a serious worldwide public health problem, and drug resistance,
particularly multidrug resistance (MDR), is a critical factor involved in TB control. We …

Molecular profiling of drug resistant isolates of Mycobacterium tuberculosis in the state of Santa Catarina, southern Brazil

RI Prim, MA Schörner, SG Senna… - Memórias do Instituto …, 2015 - SciELO Brasil
Drug resistance is a global threat and one of the main contributing factors to tuberculosis
(TB) outbreaks. The goal of this study was to analyse the molecular profile of multidrug …

Primary drug resistance among pulmonary treatment-naïve tuberculosis patients in Amazonas State, Brazil

M da Silva Garrido, R Ramasawmy… - … of tuberculosis and …, 2014 - ingentaconnect.com
BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is the main indicator of previous
treatment in tuberculosis (TB) patients. MDR-TB among treatment-naïve patients indicates …

Molecular characterisation of multidrug-resistant Mycobacterium tuberculosis isolates from a high-burden tuberculosis state in Brazil

RS Salvato, S Schiefelbein, RB Barcellos… - Epidemiology & …, 2019 - cambridge.org
Tuberculosis (TB) is the leading cause of death among infectious diseases worldwide.
Among the estimated cases of drug-resistant TB, approximately 60% occur in the BRICS …