The role of circulating tumor cells in the metastatic cascade: biology, technical challenges, and clinical relevance
Metastases and cancer recurrence are the main causes of cancer death. Circulating Tumor
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …
Circulating tumor cells: from basic to translational research
LE Cortés-Hernández, Z Eslami-S, K Pantel… - Clinical …, 2024 - academic.oup.com
Background Metastasis is the leading cause of cancer-related deaths. Most studies have
focused on the primary tumor or on overt metastatic lesions, leaving a significant knowledge …
focused on the primary tumor or on overt metastatic lesions, leaving a significant knowledge …
Circulating tumor cells (CTCs): a unique model of cancer metastases and non-invasive biomarkers of therapeutic response
Late-stage cancer metastasis remains incurable in the clinic and is the major cause death in
patients. Circulating tumor cells (CTCs) are thought to be metastatic precursors shed from …
patients. Circulating tumor cells (CTCs) are thought to be metastatic precursors shed from …
Early dissemination of circulating tumor cells: biological and clinical insights
F Chemi, S Mohan, T Guevara, A Clipson… - Frontiers in …, 2021 - frontiersin.org
Circulating tumor cells (CTCs) play a causal role in the development of metastasis, the major
cause of cancer-associated mortality worldwide. In the past decade, the development of …
cause of cancer-associated mortality worldwide. In the past decade, the development of …
Looking back, to the future of circulating tumor cells
TW Friedlander, G Premasekharan, PL Paris - Pharmacology & therapeutics, 2014 - Elsevier
Detection and analysis of circulating tumor cells (CTCs) from patients with metastatic
malignancies have become active areas of research in recent years. CTC enumeration has …
malignancies have become active areas of research in recent years. CTC enumeration has …
Circulating tumor cells as “liquid biopsies” to understand cancer metastasis
D Woo, M Yu - Translational research, 2018 - Elsevier
Circulating tumor cells (CTCs) are a subset of cancer cells that are shed from the primary or
metastatic tumors into the bloodstream. CTCs are responsible for the establishment of blood …
metastatic tumors into the bloodstream. CTCs are responsible for the establishment of blood …
Biology, detection, and clinical implications of circulating tumor cells
Cancer metastasis is the main cause of cancer‐related death, and dissemination of tumor
cells through the blood circulation is an important intermediate step that also exemplifies the …
cells through the blood circulation is an important intermediate step that also exemplifies the …
Circulating tumor cells: technologies and their clinical potential in cancer metastasis
Circulating tumor cells (CTCs) are single cells or clusters of cells within the circulatory
system of a cancer patient. While most CTCs will perish, a small proportion will proceed to …
system of a cancer patient. While most CTCs will perish, a small proportion will proceed to …
Circulating tumor cells: biology and clinical significance
D Lin, L Shen, M Luo, K Zhang, J Li, Q Yang… - Signal transduction and …, 2021 - nature.com
Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …
Circulating tumor cells: from bench to bedside
Circulating tumor cells (CTCs) represent a surrogate biomarker of hematogenous
metastases. In recent years, their detection has gained increasing interest. There is ample …
metastases. In recent years, their detection has gained increasing interest. There is ample …
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