Pulmonary inflammation is a hallmark of several pulmonary disorders including acute lung
injury and acute respiratory distress syndrome. Moreover, it has been shown that patients …

This review focuses on methods to image acute lung inflammation with Positron Emission
Tomography (PET). Four approaches are discussed that differ for biologic function of the …

Metabolic imaging is a field of molecular imaging that focuses and targets changes in
metabolic pathways for the evaluation of different clinical conditions. Targeting and …

The continued progression of chronic lung disease despite current treatment options has led
to the increasing evaluation of molecular imaging tools for diagnosis, treatment planning …

Purpose Imaging of acute lung inflammation is pivotal to evaluate innovative ventilation
strategies. We aimed to develop and validate a three-tissue compartment kinetic model …

Background Respiratory diseases are one of the leading causes of death worldwide, yet
effective treatment options remain limited. Although inflammation is thought to be a key …

Purpose This work aims to investigate lung glucose metabolism using 2-deoxy-2-[18 F]
fluoro-d-glucose ([18 F] FDG) positron emission tomography (PET) imaging in acute lung …

Acute and chronic lung diseases are almost invariably associated with some degree of
inflammation. Cells that evolved as an effective mechanism to counter infection and heal …

Lung inflammatory diseases contribute significantly to the socioeconomic burden of disease.
Yet very few new, effective therapies for respiratory disease have been approved for use. A …

Metabolic activity in the lung is known to change in response to external insults,
inflammation, and cancer. We report measurements of metabolism in the isolated, perfused …