The nonenzymatic adduction of malondialdehyde (MDA) to the protein amino groups leads
to the formation of malondialdehyde-lysine (MDALys). The degree of unsaturation of …

The nonenzymatic adduction of malondialdehyde (MDA) to the protein amino groups leads
to the formation of malondialdehyde-lysine (MDALys). The degree of unsaturation of …

Lipoperoxidation-derived aldehydes, for example malondialdehyde (MDA), can damage
proteins by generating covalent adducts whose accumulation probably participates in tissue …

Malondialdehyde (MDA) is regarded as a biomarker for oxidative stress (Del Rio et al., 2005;
Stancliffe et al., 2011), and is generated in the oxidative degradation process of …

The regulation of cell metabolism by the surrounding environment is deeply altered by the
posttranslational nonenzymatic modifications of extracellular proteins that occur throughout …

Carbonyl compounds generated by the nonenzymatic oxidation of polyunsaturated fatty
acids react with nucleophilic groups in proteins, leading to their modification. It has not been …

This article summarizes the history of Nε-(carboxymethyl) lysine (CML), from its discovery as
a product of cleavage of Amadori adducts on proteins, to its recognition as the major …

Malondialdehyde (MDA) found in the body comes from two sources: food consumed and
lipid peroxidation occurring in the tissues. The formation of MDA and the scale and rate of …

Oxidative stress is implicated in the pathogenesis of numerous disease processes including
diabetes mellitus, atherosclerosis, ischaemia reperfusion injury and rheumatoid arthritis …

Malondialdehyde (MDA) is one of several decomposition products of lipid peroxides formed
in fats and oils, in food, and in the tissues. It is the most extensively investigated of these …