The importance of post-translational glycosylation in protein structure and function has
gained significant clinical relevance recently. The latest developments in glycobiology …

Carbohydrates are the most abundant class of biomolecules and nature has made use of
these structurally complex molecules for many applications. Every living cell is covered by …

The biological relevance of glycans as mediators of key physiological processes, including
disease‐related mechanisms, makes them attractive targets for a wide range of medical …

The translation of biological glycosylation in humans to the clinical applications involves
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …

A robust platform for facile defined glycan synthesis does not exist. Yet the need for such
technology has never been greater as researchers seek to understand the full scope of …

Identifying the functional roles of carbohydrates in biological systems has been an area of
intense study in recent years. Although carbohydrates were once viewed only as inert …

This JACS Select issue highlights current and emerging areas of research at the chemistry−
glycobiology interface and illustrates how chemical and physical approaches are being …

Glycosylation of lipids and proteins is not encoded by genes directly and depends on many
factors including the origin of cell-lines, differential expression of carbohydrate enzymes and …

As modern medicine began to emerge at the turn of the 20th century, glycan-based
therapies advanced. DNA-and protein-centered therapies became widely available. The …

Protein glycosylation is a common and complex posttranslational modification of proteins,
which expands functional diversity while boosting structural heterogeneity. Glycoproteins …