Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …

Immunity and inflammation are key elements of the pathobiology of stroke, a devastating
illness second only to cardiac ischemia as a cause of death worldwide. The immune system …

The role of immunity in all stages of stroke is increasingly being recognized, from the
pathogenesis of risk factors to tissue repair, leading to the investigation of a range of …

Stroke is a major cause of morbidity and mortality worldwide. Despite the intensive search
for new therapies, hundreds of agents targeting various pathophysiological mechanisms …

Stroke is one of the leading causes of death and disability worldwide. The long‐standing
dogma that stroke is exclusively a vascular disease has been questioned by extensive …

Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …

Stroke affects the normally well-balanced interplay of the 2 supersystems: the nervous and
the immune system. Recent research elucidated some of the involved signals and …

Stroke is responsible for almost 6 million deaths and more than 10% of all mortalities each
year, and two-thirds of stroke survivors remain disabled. With treatments for ischemic stroke …

Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …

Over the past several decades, there have been substantial advances in our knowledge of
the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to …