[HTML][HTML] Comprehending meningioma signaling cascades using multipronged proteomics approaches & targeted validation of potential markers

S Mukherjee, D Biswas, R Gadre, P Jain, N Syed… - Frontiers in …, 2020 - frontiersin.org
Meningiomas are one of the most prevalent primary brain tumors. Our study aims to obtain
mechanistic insights of meningioma pathobiology using mass spectrometry-based label-free …

[HTML][HTML] Integrated Meta-Omics Analysis Unveils the Pathways Modulating Tumorigenesis and Proliferation in High-Grade Meningioma

D Biswas, A Halder, A Barpanda, S Ghosh, A Chauhan… - Cells, 2023 - mdpi.com
Meningioma, a primary brain tumor, is commonly encountered and accounts for 39% of
overall CNS tumors. Despite significant progress in clinical research, conventional surgical …

Multipronged quantitative proteomic analyses indicate modulation of various signal transduction pathways in human meningiomas

S Sharma, S Ray, S Mukherjee, A Moiyadi… - …, 2015 - Wiley Online Library
Meningiomas (MGs) are frequent tumors of the CNS originating from the meningeal layers of
the spinal cord and the brain. In this study, comparative tissue proteomic analysis of low and …

[HTML][HTML] Quantitative proteomic analysis of meningiomas for the identification of surrogate protein markers

S Sharma, S Ray, A Moiyadi, E Sridhar, S Srivastava - Scientific reports, 2014 - nature.com
Meningiomas are the most common non-glial tumors of the brain and spine.
Pathophysiology and definite histological grading of meningiomas are frequently found to be …

[HTML][HTML] Proteomic analysis discovers the differential expression of novel proteins and phosphoproteins in meningioma including NEK9, HK2 and SET and …

J Dunn, S Ferluga, V Sharma, M Futschik, DA Hilton… - …, 2019 - thelancet.com
Background Meningioma is the most frequent primary intracranial tumour. Surgical resection
remains the main therapeutic option as pharmacological intervention is hampered by poor …

[HTML][HTML] Multi-omics analysis in initiation and progression of meningiomas: from pathogenesis to diagnosis

J Liu, C Xia, G Wang - Frontiers in oncology, 2020 - frontiersin.org
Meningiomas are common intracranial tumors that can be cured by surgical resection in
most cases. However, the most disconcerting is high-grade meningiomas, which frequently …

[HTML][HTML] Integration and comparison of transcriptomic and proteomic data for meningioma

J Dunn, VP Lenis, DA Hilton, R Warta, C Herold-Mende… - Cancers, 2020 - mdpi.com
Simple Summary Meningioma are the most common primary intracranial tumour, yet gaps in
their molecular characterisation persist and effective treatments for aggressive, recurring …

Comprehensive proteomic analysis reveals distinct functional modules associated with skull base and supratentorial meningiomas and perturbations in collagen …

S Mukherjee, D Biswas, S Epari, P Shetty, A Moiyadi… - Journal of …, 2021 - Elsevier
Meningiomas are brain tumors that originate from the meninges and has been primarily
classified into three grades by the current WHO guidelines. Although widely prevalent and …

Phosphoproteomic and kinomic signature of clinically aggressive grade i (1.5) meningiomas reveals RB1 signaling as a novel mediator and biomarker

CA Parada, JW Osbun, T Busald, Y Karasozen… - Clinical Cancer …, 2020 - AACR
Abstract Purpose: Most World Health Organization (WHO) grade I meningiomas carry a
favorable prognosis. Some become clinically aggressive with recurrence, invasion, and …

Proteomic analysis of meningiomas reveals clinically distinct molecular patterns

MD Papaioannou, U Djuric, J Kao, S Karimi… - Neuro …, 2019 - academic.oup.com
Background Meningiomas represent one of the most common brain tumors and exhibit a
clinically heterogeneous behavior, sometimes difficult to predict with classic histopathologic …