In patients with ARDS, optimal PEEP should not be determined using the intersection of relative collapse and relative overdistention

M van den Berg, H van der Hoeven - American Journal of …, 2020 - atsjournals.org
With great interest, we read the article by van der Zee and colleagues suggesting an
individualized approach for setting the correct amount of positive end-expiratory pressure …

Increasing Positive End-Expiratory Pressure to Recruit the Lungs: Take into Account Heart–Lung Interaction and Oxygen Delivery

V Le Stang, M Dres - American Journal of Respiratory and Critical …, 2023 - atsjournals.org
We have read with great interest the article by Jonkman et al., entitled" Lung Recruitment
assessed by Electrical Impedance Tomography (RECRUIT): a multicenter study of COVID …

Electrical impedance tomography for positive end-expiratory pressure titration in COVID-19–related acute respiratory distress syndrome

P van der Zee, P Somhorst, H Endeman… - American journal of …, 2020 - atsjournals.org
Methods Study design and inclusion criteria. We conducted this case series between March
1, 2020, and March 31, 2020, in our tertiary referral ICU (Erasmus Medical Center …

Electrical Impedance Tomography and Optimal Positive End-Expiratory Pressure: Uncovering Latent Heterogeneity of Treatment Effect

JV Jimenez, RC Hyzy - American Journal of Respiratory and Critical …, 2023 - atsjournals.org
We read with great interest the study by Jonkman and colleagues (1), who performed a
multicenter observational trial in COVID-19 patients with ARDS utilizing electrical …

Lung recruitment assessed by electrical impedance tomography (RECRUIT): a multicenter study of COVID-19 acute respiratory distress syndrome

AH Jonkman, GC Alcala, B Pavlovsky… - American Journal of …, 2023 - atsjournals.org
Rationale: Defining lung recruitability is needed for safe positive end-expiratory pressure
(PEEP) selection in mechanically ventilated patients. However, there is no simple bedside …

Maximal lung recruitment in acute respiratory distress syndrome: a nail in the coffin

J Mancebo, A Mercat, L Brochard - American journal of respiratory …, 2019 - atsjournals.org
The traditional way to reverse hypoxemia in acute respiratory distress syndrome (ARDS) is
the use of positive end-expiratory pressure (PEEP). Ideally, PEEP is to be used to maximize …

Effect of positive end-expiratory pressure and proning on ventilation and perfusion in COVID-19 acute respiratory distress syndrome

F Perier, S Tuffet, T Maraffi, G Alcala… - American journal of …, 2020 - atsjournals.org
Methods ARDS was defined according to the Berlin definition (1), and severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was confirmed by positive …

Lung-dependent areas collapse, monitored by electrical impedance tomography, may predict the oxygenation response to prone ventilation in COVID-19 acute …

M Cardinale, S Boussen, PJ Cungi, P Esnault… - Critical Care …, 2022 - journals.lww.com
OBJECTIVES: ICUs have had to deal with a large number of patients with acute respiratory
distress syndrome COVID-19, a significant number of whom received prone ventilation …

PEEP titration is markedly affected by trunk inclination in mechanically ventilated patients with COVID-19 ARDS: a physiologic, cross-over study

F Marrazzo, S Spina, F Zadek, C Forlini… - Journal of Clinical …, 2023 - mdpi.com
Background: Changing trunk inclination affects lung function in patients with ARDS.
However, its impacts on PEEP titration remain unknown. The primary aim of this study was to …

Lung recruitability and positive end-expiratory pressure setting in ARDS caused by COVID-19

DL Grieco, G De Pascale, M Antonelli - Chest, 2022 - journal.chestnet.org
In ARDS, mechanical ventilation represents the milestone treatment to restore adequate gas
exchange but may itself aggravate lung damage by ventilatorinduced lung injury because …