Family with sequence similarity 20, member C (FAM20C) is the main kinase of secreted
phosphoproteins, including the multifunctional protein and cytokine, osteopontin (OPN). The …

Objective Osteopontin (OPN) is a well-known glycoprotein involved in numerous
pathobiological processes, including cancer. Despite having five splice variants for …

Osteopontin (OPN) is a secreted phosphoprotein involved in cellular proliferation and
associated with tumor progression. Although an intracellular form of OPN has been …

Among osteopontin splice variants (OPN-SV), the expression profile of osteopontin-4
(OPN4) and osteopontin-5 (OPN5) has not been addressed in distinct cancer types. We …

Fam20C, which phosphorylates many secretory proteins with SxE/pS motifs, is highly
expressed in bone and tooth tissues, implying that Fam20C-mediated phosphorylation is …

Osteopontin (OPN), a multifunctional glycoprotein, has three transcripts that have distinct
roles in tumors in vitro. Whether OPN transcripts have different functions in tumor processes …

Osteopontin (OPN) is a matricellular protein that binds to a number of cell surface receptors
including integrins and CD44. It is expressed in many tissues and secreted into body fluids …

Osteopontin (OPN) is a highly acidic secreted phosphoprotein that binds to cells via an RGD
(arginine-glycine-aspartic acid) cell adhesion sequence that recognizes the αVβ3 integrin …

Background Osteopontin is a secreted, integrin-binding and phosphorylated acidic
glycoprotein which has an important role in tumor progression. Findings In this study, we …

Osteopontin (OPN) is a secreted glycoprotein produced by osteoclasts, macrophages, T
cells, hematopoietic cells, and vascular smooth muscle cells. It contributes to macrophage …