Mass spectrometry-based technology and workflows for studying the chemistry of fungal endophyte derived bioactive compounds
Bioactive compounds have gained substantial attention in research and have conferred
great advancements in the industrial and pharmacological fields. Highly diverse fungi and …
great advancements in the industrial and pharmacological fields. Highly diverse fungi and …
[HTML][HTML] Natural products dereplication by diffusion ordered NMR spectroscopy (DOSY)
Diffusion-ordered NMR spectroscopy (DOSY) can be used to analyze mixtures of
compounds since resonances deriving from different compounds are distinguished by their …
compounds since resonances deriving from different compounds are distinguished by their …
Sarcaglarols A—D, Lindenane−Monoterpene Heterodimers from Sarcandra glabra Based on Molecular Networks
Y Wang, Z Cui, J Chi, P Tang, M Zhang… - Chinese Journal of …, 2021 - Wiley Online Library
Main observation and conclusion Sarcaglarols A—D (1—4), two pairs of lindenane−
monoterpene heterodimers fused by a 1, 2‐dioxane moiety, were discovered and isolated …
monoterpene heterodimers fused by a 1, 2‐dioxane moiety, were discovered and isolated …
[HTML][HTML] Metabolomics as a tool to study underused soy parts: In search of bioactive compounds
The valorization of agri-food by-products is essential from both economic and sustainability
perspectives. The large quantity of such materials causes problems for the environment; …
perspectives. The large quantity of such materials causes problems for the environment; …
Predicting biochemical and physiological effects of natural products from molecular structures using machine learning
J Jeon, S Kang, HU Kim - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2016 to 2021 Discovery of novel natural products has been greatly facilitated by
advances in genome sequencing, genome mining and analytical techniques. As a result, the …
advances in genome sequencing, genome mining and analytical techniques. As a result, the …
[HTML][HTML] Insulin-Mimic Components in Acer truncatum Leaves: Bio-Guided Isolation, Annual Variance Profiling and Regulating Pathway Investigated by Omics
XY Zhang, YH Liu, DZ Liu, JY Xu, Q Zhang - Pharmaceuticals, 2021 - mdpi.com
Insulin mimic can promote transporting glucose to muscle tissue and accelerate glucose
consumption. It is commonly occurring in many functional foods or traditional medicines. Anti …
consumption. It is commonly occurring in many functional foods or traditional medicines. Anti …
Vibsane-type diterpenoids from Viburnum odoratissimum and their cytotoxic activities
SF Li, XQ Yu, YL Li, M Bai, B Lin, GD Yao, SJ Song - Bioorganic Chemistry, 2021 - Elsevier
Abstract Seven new diterpenoids (1–7), including five 7-membered ring vibsane-type
diterpenoids, vibsanolide AE (1–5) and a pair of epimers of 14, 15, 16, 17-tetranorvibsane …
diterpenoids, vibsanolide AE (1–5) and a pair of epimers of 14, 15, 16, 17-tetranorvibsane …
Combining NMR-based metabolic profiling and genome mining for the accelerated discovery of Archangiumide, an Allenic Macrolide from the Myxobacterium …
JQ Hu, JJ Wang, YL Li, L Zhuo, A Zhang, HY Sui… - Organic …, 2021 - ACS Publications
An unprecedented 19-membered allenic macrolide archangiumide (1) was discovered from
the myxobacterium Archangium violaceum SDU8 by integrating NMR-based metabolic …
the myxobacterium Archangium violaceum SDU8 by integrating NMR-based metabolic …
[HTML][HTML] Biocatalytic synthesis of peptidic natural products and related analogues
Peptidic natural products (PNPs) represent a rich source of lead compounds for the
discovery and development of therapeutic agents for the treatment of a variety of diseases …
discovery and development of therapeutic agents for the treatment of a variety of diseases …
[HTML][HTML] Metabolomics-guided elucidation of plant abiotic stress responses in the 4IR era: An Overview
Plants are constantly challenged by changing environmental conditions that include abiotic
stresses. These are limiting their development and productivity and are subsequently …
stresses. These are limiting their development and productivity and are subsequently …