Marine biodiscovery in a changing world

MM Reddy, L Jennings, OP Thomas - Progress in the Chemistry of Organic …, 2021 - Springer
The term “marine biodiscovery” has been recently been adopted to describe the area of
marine natural products dedicated to the search of new drugs. Several maritime countries …

Isolation and Total Synthesis of Bromoiesol sulfates, Antitrypanosomal arylethers from a Salileptolyngbya sp. Marine Cyanobacterium

A Ebihara, A Iwasaki, Y Miura, G Jeelani… - The Journal of …, 2021 - ACS Publications
Bromoiesol sulfates A (1) and B (2), new polyhalogenated aryl sulfates, were isolated from a
Salileptolyngbya sp. marine cyanobacterium along with their hydrolyzed compounds …

[HTML][HTML] Coupling mass spectral and genomic information to improve bacterial natural product discovery workflows

M Crüsemann - Marine Drugs, 2021 - mdpi.com
Bacterial natural products possess potent bioactivities and high structural diversity and are
typically encoded in biosynthetic gene clusters. Traditional natural product discovery …

Speech-based solution to Parkinson's disease management

B Sonawane, P Sharma - Multimedia Tools and Applications, 2021 - Springer
Parkinson's disease (PD) is a neurological disorder marked by decreased dopamine levels
in the brain. Persons suffering from PD, exhibits vocal symptoms such as dysphonia and …

[PDF][PDF] A supervised fingerprint-based strategy to connect natural product mass spectrometry fragmentation data to their biosynthetic gene clusters

TF Leao, M Wang, R da Silva, JJJ van der Hooft - Significance, 2021 - researchgate.net
Microbial natural products, in particular secondary or specialized metabolites, are an 25
important source and inspiration for many pharmaceutical and biotechnological products. 26 …

[HTML][HTML] Genomic scanning enabling discovery of a new antibacterial bicyclic carbamate-containing alkaloid

Q Fang, L Wu, C Urwald, M Mugat, S Wang… - Synthetic and Systems …, 2021 - Elsevier
Non-ribosomal peptides are a group of structurally diverse natural products with various
important therapeutic and agrochemical applications. Bacterial pyrrolizidine alkaloids (PAs) …

[HTML][HTML] (Des) Construindo a Metabolômica Em Produtos Naturais: Um Convite a Discussão

RM Borges, JVM Resende - Química Nova, 2021 - SciELO Brasil
The metabolomics approach is widespread and accepted in several lines within life
sciences. However, much of what has been called metabolomics could be better defined as …

Spatial Identification of Vulnerable Coastal Ecosystems for Emerging Pollutants

A Kumari, R Harshawardhan, J Kushawaha… - … , current challenges and …, 2021 - Springer
Coastal ecosystems play a crucial role in maintaining ecosystem services. These also
harbor diverse groups of flora and fauna. Increased anthropogenic activities are degrading …

Two New Alkaloids from Fuzi and Their Metabolites Study

S Liu, P Deng, Y Long, S Yang, J Zhu, K Li… - Chemistry & …, 2021 - Wiley Online Library
Former study suggests alkaloids from herbs of Aconitum genus plants possess excellent
bioactivities, which exert great value for related deeper chemical constituent investigation …

Essential Terminology Connects NMR and qNMR Spectroscopy to its Theoretical Foundation

G Pauli, GJ Ray, A Bzhelyansky, B Jaki, C Corbett… - 2021 - chemrxiv.org
Classical 1D 1H NMR spectra are prototypic for NMR spectroscopy in that they represent a
wealth of chemical information encoded into convoluted graphs or patterns that contain …