Genome-wide association studies have identified single nucleotide polymorphisms (SNPs)
associated with schizophrenia risk. Integration of RNA-sequencing data from postmortem …

Visuospatial working memory (vsWM) requires information transfer among multiple cortical
regions, from primary visual (V1) to prefrontal (PFC) cortices. This information is conveyed …

Tremendous work has demonstrated the critical roles of genetics, epigenetics as well as
their interplay in brain transcriptional regulations in the pathology of schizophrenia (SZ) …

Neurons derived from human induced pluripotent stem cells (hiPSCs) have been used to
model basic cellular aspects of neuropsychiatric disorders, but the relationship between the …

While large-scale genome-wide association studies (GWAS) have identified hundreds of loci
associated with neuropsychiatric and neurodegenerative traits, identifying the variants …

Genome-wide association studies (GWAS) have accelerated the discovery of numerous
genetic variants associated with schizophrenia. However, most risk variants show a small …

Background Bipolar disorder (BD) is a severe psychiatric illness attributable to multifactorial
risk components (eg environmental stimuli, neuroinflammation, etc.), and genetic variations …

Alternative splicing of RNA transcripts allows a single gene to generate multiple products
and is a key means of generating functionally diverse voltage-gated ion channels. Splicing …

Variants identified by genome‐wide association studies (GWAS) are often expression
quantitative trait loci (eQTLs), suggesting they are proxies or are themselves regulatory …

Background: Shared psychopathological features and mechanisms have been observed
between schizophrenia (SZ) and bipolar disorder (BD), but their common risk genes and full …