Cell type-specific biotin labeling in vivo resolves regional neuronal proteomic differences in mouse brain

S Rayaprolu, S Bitarafan, R Betarbet, S Sunna… - BioRxiv, 2021 - biorxiv.org
Isolation and proteomic profiling of brain cell types, particularly neurons, pose several
technical challenges which limit our ability to resolve distinct cellular phenotypes in …

Single-cell RNA transcriptome analysis reveals CXCL16/CXCR6 as maintenance factors for CNS tissue resident T cells that drive synapse elimination during viral …

SF Rosen, AL Soung, W Yang, S Ai, M Kanmogne… - bioRxiv, 2021 - biorxiv.org
Background Emerging RNA viruses that target the central nervous system (CNS) lead to
cognitive sequelae in survivors. Studies in humans and mice infected with West Nile virus …

Ureter single-cell and spatial mapping reveal cell types, architecture, and signaling networks

EE Fink, S Sona, U Tran, PE Desprez, M Bradley, H Qiu… - bioRxiv, 2021 - biorxiv.org
Tissue engineering offers a promising treatment strategy for ureteral strictures, but its
success requires an in-depth understanding of the architecture, cellular heterogeneity, and …

Single Cell RNA Sequencing (scRNA-Seq) as an Emerging Technology in Cancer Research: Applications of scRNA-seq in cancer research

AU Rehman, A Rashid, I Anwar - … of the Pakistan Academy of Sciences …, 2021 - ppaspk.org
RNA sequencing (RNA-seq) has revolutionized basic biomedical research by studying the
transcriptome at high resolution, and thus it has been proved to be very successful for …

Targeting Endogenous Homeostatic Mechanisms For The Treatment Of Cocaine Use Disorder: Contribution Of Nr4a1 And Target Gene Expression

MD Carpenter - 2021 - search.proquest.com
Cocaine use disorder continues to be a worldwide public health problem and currently there
are no approved medications for its treatment. Decades of research have identified a …

A multimodal cell census and atlas of the mammalian primary motor cortex

A Regev - 2021 - dspace.mit.edu
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …

[PDF][PDF] TOWARD SINGLE-NEURON MORPHOLOGY OF NEUROMODULATORY SYSTEMS

AM Martins - 2021 - jscholarship.library.jhu.edu
The flow of information within the brain is determined by neuronal cell types and their
morphology, which control how signals are routed in the mammalian brain. These signals …

[图书][B] Integrated computational analysis of brain cell transcriptomes and epigenomes

F Xie - 2021 - search.proquest.com
The mammalian brain consists of a vast network of neurons and non-neuronal cells with
diverse morphology, anatomy, physiology and behavioral roles. These cellular phenotypes …