Engineering heterogeneity of precision nanoparticles for biomedical delivery and therapy

D Zheng, K Yang, Z Nie - View, 2021 - Wiley Online Library
Nanoparticle (NP)‐based vehicles are attractive for biomedical delivery and therapy, owing
to improved therapeutic efficiency and reduced adverse effects compared to free drugs …

Oxidative stress and antioxidant nanotherapeutic approaches for inflammatory bowel disease

P Liu, Y Li, R Wang, F Ren, X Wang - Biomedicines, 2021 - mdpi.com
Oxidative stress, caused by the accumulation of reactive species, is associated with the
initiation and progress of inflammatory bowel disease (IBD). The investigation of …

Can bilirubin nanomedicine become a hope for the management of COVID-19?

I Khurana, P Allawadhi, A Khurana, AK Srivastava… - Medical …, 2021 - Elsevier
Bilirubin has been proven to possess significant anti-inflammatory, antioxidant and antiviral
activities. Recently, it has been postulated as a metabolic hormone. Further, moderately …

Redox-active nanoparticles for inflammatory bowel disease

Q Ren, S Sun, XD Zhang - Nano Research, 2021 - Springer
Homeostasis of gut microbiota is extremely essential for maintaining nutrient metabolism
and regulating immunological function. The increasing evidence suggests that inflammatory …

Commensal flora triggered target anti-inflammation of alginate-curcumin micelle for ulcerative colitis treatment

Y Wang, Y Li, L He, B Mao, S Chen, V Martinez… - Colloids and Surfaces B …, 2021 - Elsevier
Ulcerative colitis (UC) is a chronic, idiopathic inflammatory bowel disease characterized by
dysregulation of colon immune response. Curcumin (Cur) has strong anti-inflammatory …

Oral delivery of biologics in inflammatory bowel disease treatment

W Zhang, CB Michalowski, A Beloqui - Frontiers in Bioengineering …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) has been posed as a great worldwide health threat.
Having an onset during early adulthood, IBD is a chronic inflammatory disease …

Aminocellulose-grafted polycaprolactone-coated core–shell nanoparticles alleviate the severity of ulcerative colitis: a novel adjuvant therapeutic approach

A Ahmad, MM Ansari, A Kumar, M Bishnoi… - Biomaterials …, 2021 - pubs.rsc.org
Ulcerative colitis (UC) is an idiopathic inflammatory condition of colorectal regions. Existing
therapies for UC face grave lacunae including off-target and other harmful side effects …

Self‐assembling bile pigments for cancer diagnosis and therapy

K Chen, R Xing, X Yan - Aggregate, 2021 - Wiley Online Library
Nanomaterials that integrate multiple functions provide promising opportunities for
noninvasive and targeted cancer diagnosis and therapy. However, the unclear metabolic …

Targeting strategies of oral nano-delivery systems for treating inflammatory bowel disease

W Liu, Z Dong, K Liu, Y Lu, W Wu, J Qi… - International Journal of …, 2021 - Elsevier
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder of
gastrointestinal tract with rising incidence. Established treatments of IBD are characterized …

Hyaluronan: a neuroimmune modulator in the microbiota-gut axis

A Bosi, D Banfi, M Bistoletti, P Moretto, E Moro… - Cells, 2021 - mdpi.com
The commensal microbiota plays a fundamental role in maintaining host gut homeostasis by
controlling several metabolic, neuronal and immune functions. Conversely, changes in the …