It is now appreciated that a group of lymphoid lineage cells, collectively called innate-like
effector lymphocytes, have evolved to integrate information relayed by the innate sensory …

Interleukin 2 is essential for the expansion of regulatory T cells, and low-dose recombinant
interleukin 2 has improved the clinical manifestations of diverse autoimmune diseases in …

Cluster of differentiation 1 (CD1) is a family of cell-surface glycoproteins that present lipid
antigens to T cells. Humans have five CD1 isoforms. CD1a is distinguished by the small …

Natural killer T (NKT) cells constitute a unique subset of T lymphocytes characterized by
specifically interacting with antigenic glycolipids conjugated to the CD1d receptor on antigen …

Invariant natural killer T (iNKT) cells mediate rapid immune responses which bridge the gap
between innate and adaptive responses to pathogens while also providing key regulation to …

Natural killer T (NKT) cells are an abundant subset of liver lymphocytes activated by lipid
antigens presented on CD1d molecules that are expressed by cholangiocytes. We aimed to …

Problem Acute chorioamnionitis (aCAM) associated with microbial infection is a primary
cause of preterm birth (PB). However, recent studies have demonstrated that innate …

Rationale: Invariant natural killer T (iNKT) cells and Kupffer cells represent major hepatic
populations of innate immune cells. However, their roles in steatohepatitis remain poorly …

Treatment with a reduced dose of glucocorticoids (0.5 mg/kg per day) in addition to rituximab
was non-inferior to treatment with high-dose glucocorticoids (1 mg/kg per day) plus rituximab …

Innate-like T cells, including invariant natural killer T (iNKT) cells, mucosal-associated
invariant T (MAIT) cells and γδ T cells, are present in various barrier tissues, including the …