Alzheimer's disease (AD), the most common form of dementia in elderly individuals, is
marked by progressive neuron loss. Despite more than 100 years of research on AD, there …

Objective Recent clinical trials targeting amyloid beta (Aβ) and tau in Alzheimer's disease
(AD) have yet to demonstrate efficacy. Reviewing the hypotheses for AD pathogenesis and …

Abstract Late Onset Alzheimer's Disease is the most common cause of dementia,
characterized by extracellular deposition of plaques primarily of amyloid-β (Aβ) peptide and …

Abstract tRNA-derived fragments (tRFs), which by definition are cleaved from tRNAs,
comprise a novel class of regulatory small non-coding RNAs. Recent evidence has revealed …

Radiation exposure may induce Alzheimer's disease (AD), depression or schizophrenia. A
number of experimental and clinical studies suggest the involvement of miRNA in the …

Background: Iron trafficking and accumulation is associated with Alzheimer's disease (AD)
pathogenesis. However, the role of iron dyshomeostasis in early disease stages is …

Introduction: Alzheimer's disease (AD) is the most common neurodegenerative disorder and
the primary form of dementia in the elderly. Changes in DNA methylation and post …

Dementia is described as the fifth leading cause of death worldwide and Alzheimer's
disease (AD) is recognized as the most common, causing a huge impact on health costs and …

Neurodegenerative diseases are etiologically and clinically heterogeneous conditions, often
reflecting a spectrum of disease rather than well-defined disorders. The underlying …

Fragile X mental retardation protein (FMRP) is an RNA binding protein (RBP) whose
absence is essentially associated to Fragile X Syndrome (FXS). As an RNA Binding Protein …