[HTML][HTML] Recombinant porcine factor VIII: Lessons from the past and place in the management of hemophilia A with inhibitors in 2021

Y Dargaud, C Escuriola‐Ettingshausen - Research and Practice in …, 2021 - Elsevier
The most serious complication of factor VIII (FVIII) replacement therapy is the occurrence of
anti‐FVIII alloantibodies that can strongly reduce or abolish the effect of human FVIII …

Ex vivo prediction of comprehensive coagulation potential using simulated blood concentrations of emicizumab in patients with acquired hemophilia A

M Takeyama, S Furukawa, K Yada… - Thrombosis and …, 2021 - thieme-connect.com
Introduction Emicizumab prophylaxis improves coagulation function in congenital
hemophilia A, regardless of inhibitor presence. We recently reported that emicizumab …

Principles of care for acquired hemophilia

G Dolan, G Benson, A Bowyer, H Eichler… - European journal of …, 2021 - Wiley Online Library
Objective To establish clear priorities for the care of patients with acquired hemophilia A
(AHA) by proposing 10 key principles of practical, holistic AHA management. Method These …

Emicizumab in acquired haemophilia A: about two clinical cases and literature review

A Hansenne, C Hermans - Therapeutic advances in …, 2021 - journals.sagepub.com
Acquired haemophilia A (AHA) is a rare and severe haemorrhagic autoimmune disease
caused by autoantibodies directed against factor VIII (FVIII). Treatment is based on two …

[HTML][HTML] Immunoadsorption for the treatment of acquired hemophilia: new observational data, systematic review, and meta-analysis

ME Pereira, C Bocksrucker, JAK Hovinga… - Transfusion medicine …, 2021 - Elsevier
The treatment of patients with acquired hemophilia is challenging due to life-threatening
hemorrhages, delayed response, and adverse effects to immunosuppressive agents. Even …

[HTML][HTML] Predictive significance of anti‐FVIII immunoglobulin patterns on bleeding phenotype and outcomes in acquired hemophilia A: Results from the Quebec …

A Bonnefoy, C Merlen, E Dubé… - Journal of Thrombosis …, 2021 - Elsevier
Abstract Background Acquired hemophilia A (AHA) is a potentially life‐threatening bleeding
disorder caused by factor VIII (FVIII) autoantibodies, involving various immunoglobulin (Ig) …

Bullous pemphigoid is a common associated disorder with acquired haemophilia A

NA Abdul-Halim, HJ Ng - International Journal of Hematology, 2021 - Springer
Although the estimated incidence of acquired haemophilia A (AHA) in Singapore is similar to
those reported in the literature, we have observed differences in the frequency of their …

Diagnosis and management of acquired hemophilia a: case reports and a literature review

I Rinaldi, F Prasetyawaty, S Fazlines… - Case reports in …, 2021 - Wiley Online Library
Background. Acquired hemophilia A (AHA) is a potentially life‐threatening autoimmune
hemostatic disorder where autoantibodies that disrupt the functions of factor VIII (FVIII) are …

[HTML][HTML] Characteristics of acquired inhibitors to factor VIII and von Willebrand factor secondary to systemic lupus erythematosus: experiences from a Chinese tertiary …

XY Cao, MT Li, X Zhang, Y Zhao, XF Zeng… - JCR: Journal of …, 2021 - journals.lww.com
Objective Because acquired hemophilia (AH) is a rare entity in systemic lupus
erythematosus (SLE), we aimed to investigate the clinical features of SLE-related AH in …

[HTML][HTML] Consenso de hemofilia en México

JL López-Arroyo, JM Pérez-Zúñiga… - Gaceta médica de …, 2021 - scielo.org.mx
Consenso de hemofilia en México SciELO - Scientific Electronic Library Online vol.157 suppl.1
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