Gliomas are heavily infiltrated with immune cells of myeloid origin. Past studies have shown
that high-grade gliomas have a higher proportion of alternatively activated and suppressive …

The testing of new neoadjuvant therapeutic strategies for operable non-small-cell lung
cancer (NSCLC) has rapidly progressed as it has benefitted from the practicechanging …

Gliomas are diffusely growing tumours arising from progenitors within the central nervous
system. They encompass a range of different molecular types and subtypes, many of which …

The diagnostic role of Isocitrate Dehydrogenase (IDH) mutation status in adult lower grade
astrocytomas was first formally presented within the WHO Classification of Tumours of the …

Background Recent large-scale genomic studies have revealed a spectrum of genetic
variants associated with specific subtypes of central nervous system (CNS) tumors. The aim …

Background Diffuse gliomas are the most frequent primary tumors originating in the central
nervous system parenchyma. Although the majority of these tumors are highly malignant …

Purpose: This study aimed to assess the relationship between mean kurtosis (MK) and
mean diffusivity (MD) values from whole-brain diffusion kurtosis imaging (DKI) parametric …

In clinical practice, the trade-off between efficacy and (acute and long-term) toxicity of
treatments needs to be re-evaluated for the newly (molecularly) defined entities. Updates …

Résumé Les tumeurs gliales et glioneuronales, même si rares par rapport aux tumeurs extra-
crâniennes, sont à l'origine d'une morbidité et mortalité importantes. L'Organisation …

Molecular testing has become part of the routine diagnostic workup of brain tumors after the
implementation of integrated histomolecular diagnoses in the 2016 WHO classification …